Effects of Thermoextracts of Brucella S and L Forms on Lipid Peroxidation and Antioxidant Defense in Organs of Laboratory Animals

V. I. Dubrovina; S. V. Balakhonov; O. V. Yurieva; T. P. Starovoitova; N. L. Barannikova; L. E. Tokareva; A. B. Pyatidesyatnikova; K. Yu. Yastremskaya; T. T. Shkaruba

doi:10.1007/s10517-018-4138-2

Effects of Thermoextracts of Brucella S and L Forms on Lipid Peroxidation and Antioxidant Defense in Organs of Laboratory Animals

Авторлар: Dubrovina V.¹, Balakhonov S.¹, Yurieva O.¹, Starovoitova T.¹, Barannikova N.¹, Tokareva L.¹, Pyatidesyatnikova A.¹, Yastremskaya K.¹, Shkaruba T.¹
Мекемелер:
1. Irkutsk Antiplague Research Institute of Siberia and Far East
Шығарылым: Том 165, № 2 (2018)
Беттер: 239-242
Бөлім: Article
URL: https://journals.rcsi.science/0007-4888/article/view/240193
DOI: https://doi.org/10.1007/s10517-018-4138-2
ID: 240193

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат
Рұқсат жабық

Рұқсат берілді
Рұқсат жабық

Тек жазылушылар үшін

Аннотация
Авторлар туралы
Әдебиет тізімі
Статистика

Аннотация

The dynamics of LPO marker malondialdehyde formation and peroxidase-destroying activity was studied in homogenized organs of guinea pigs, immunized with thermoextracts from S and L forms Brucella abortus I-206. The L form brucella thermoextract exhibited a lower reactogenicity and adequately activated the antioxidant system, due to which the destructive effects of ROS could be partially neutralized during the vaccinal process.