Effects of Thermoextracts of Brucella S and L Forms on Lipid Peroxidation and Antioxidant Defense in Organs of Laboratory Animals

V. I. Dubrovina; S. V. Balakhonov; O. V. Yurieva; T. P. Starovoitova; N. L. Barannikova; L. E. Tokareva; A. B. Pyatidesyatnikova; K. Yu. Yastremskaya; T. T. Shkaruba

doi:10.1007/s10517-018-4138-2

Effects of Thermoextracts of Brucella S and L Forms on Lipid Peroxidation and Antioxidant Defense in Organs of Laboratory Animals

Autores: Dubrovina V.¹, Balakhonov S.¹, Yurieva O.¹, Starovoitova T.¹, Barannikova N.¹, Tokareva L.¹, Pyatidesyatnikova A.¹, Yastremskaya K.¹, Shkaruba T.¹
Afiliações:
1. Irkutsk Antiplague Research Institute of Siberia and Far East
Edição: Volume 165, Nº 2 (2018)
Páginas: 239-242
Seção: Article
URL: https://journals.rcsi.science/0007-4888/article/view/240193
DOI: https://doi.org/10.1007/s10517-018-4138-2
ID: 240193

Citar

Texto integral

Acesso aberto
Acesso é fechado

Acesso está concedido
Acesso é fechado

Somente assinantes

Resumo
Sobre autores
Bibliografia
Estatísticas

Resumo

The dynamics of LPO marker malondialdehyde formation and peroxidase-destroying activity was studied in homogenized organs of guinea pigs, immunized with thermoextracts from S and L forms Brucella abortus I-206. The L form brucella thermoextract exhibited a lower reactogenicity and adequately activated the antioxidant system, due to which the destructive effects of ROS could be partially neutralized during the vaccinal process.