Cardiovascular Effects of High-Molecular-Weight Compounds of Humic Nature
- Авторлар: Zykova M.1, Belousov M.1, Lasukova T.2,3, Gorbunov A.3, Logvinova L.1, Dygai A.4
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Мекемелер:
- Siberian State Medical University, Ministry of Health of the Russian Federation
- Tomsk State Pedagogical University, Ministry of Science and Education
- Research Institute of Cardiology
- E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
- Шығарылым: Том 163, № 2 (2017)
- Беттер: 206-209
- Бөлім: Pharmacology and Toxicology
- URL: https://journals.rcsi.science/0007-4888/article/view/238755
- DOI: https://doi.org/10.1007/s10517-017-3767-1
- ID: 238755
Дәйексөз келтіру
Аннотация
The active ingredient extracted from the peat humic substances was characterized by physicochemical parameters evaluated by UV- and IR-spectroscopy, titration, and elemental (C, H, N) analysis. The cardiovascular effects of this ingredient were examined on isolated Langendorff-perfused rat heart. It was found that the active substance in a concentration range of 0.01-0.1 mg/ml produced a vasodilating effect; in addition, it decreased the end-diastolic and left-ventricular developed pressures.
Авторлар туралы
M. Zykova
Siberian State Medical University, Ministry of Health of the Russian Federation
Хат алмасуға жауапты Автор.
Email: gmv2@rambler.ru
Ресей, Tomsk
M. Belousov
Siberian State Medical University, Ministry of Health of the Russian Federation
Email: gmv2@rambler.ru
Ресей, Tomsk
T. Lasukova
Tomsk State Pedagogical University, Ministry of Science and Education; Research Institute of Cardiology
Email: gmv2@rambler.ru
Ресей, Tomsk; Tomsk
A. Gorbunov
Research Institute of Cardiology
Email: gmv2@rambler.ru
Ресей, Tomsk
L. Logvinova
Siberian State Medical University, Ministry of Health of the Russian Federation
Email: gmv2@rambler.ru
Ресей, Tomsk
A. Dygai
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences
Email: gmv2@rambler.ru
Ресей, Tomsk