Мақаланы E-mail арқылы жіберу Antihypoxic and Neuroprotective Effects of Glial Cell-Derived Neurotrophic Factor (GDNF) in Cultures of Dissociated Hippocampal Cells under Conditions of Experimental Hypoxia
- Авторлар: Vedunova M.1,2, Shishkina T.1,2, Mishchenko T.1,2, Mitroshina E.1,2, Astrakhanova T.1, Pimashkin A.1, Mukhina I.1,2
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Мекемелер:
- N. I. Lobachevsky Nizhny Novgorod State University
- Nizhny Novgorod State Medical Academy, Ministry of Health of the Russian Federation
- Шығарылым: Том 161, № 1 (2016)
- Беттер: 168-174
- Бөлім: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/237237
- DOI: https://doi.org/10.1007/s10517-016-3369-3
- ID: 237237
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
We analyzed the effect of glial cell derived neurotrophic factor (GDNF) on changes in functional bioelectric and calcium activity in dissociated hippocampal cell cultures under conditions of modeled acute normobaric hypoxia in vitro. GDNF (1 ng/ml) partially neutralized the negative effects of hypoxia on cell survival and parameters of functional network activity. GDNF exhibited a pronounced anti-hypoxic effect.
Авторлар туралы
M. Vedunova
N. I. Lobachevsky Nizhny Novgorod State University; Nizhny Novgorod State Medical Academy, Ministry of Health of the Russian Federation
Хат алмасуға жауапты Автор.
Email: mvedunova@yandex.ru
Ресей, Nizhny Novgorod; Nizhny Novgorod
T. Shishkina
N. I. Lobachevsky Nizhny Novgorod State University; Nizhny Novgorod State Medical Academy, Ministry of Health of the Russian Federation
Email: mvedunova@yandex.ru
Ресей, Nizhny Novgorod; Nizhny Novgorod
T. Mishchenko
N. I. Lobachevsky Nizhny Novgorod State University; Nizhny Novgorod State Medical Academy, Ministry of Health of the Russian Federation
Email: mvedunova@yandex.ru
Ресей, Nizhny Novgorod; Nizhny Novgorod
E. Mitroshina
N. I. Lobachevsky Nizhny Novgorod State University; Nizhny Novgorod State Medical Academy, Ministry of Health of the Russian Federation
Email: mvedunova@yandex.ru
Ресей, Nizhny Novgorod; Nizhny Novgorod
T. Astrakhanova
N. I. Lobachevsky Nizhny Novgorod State University
Email: mvedunova@yandex.ru
Ресей, Nizhny Novgorod
A. Pimashkin
N. I. Lobachevsky Nizhny Novgorod State University
Email: mvedunova@yandex.ru
Ресей, Nizhny Novgorod
I. Mukhina
N. I. Lobachevsky Nizhny Novgorod State University; Nizhny Novgorod State Medical Academy, Ministry of Health of the Russian Federation
Email: mvedunova@yandex.ru
Ресей, Nizhny Novgorod; Nizhny Novgorod
