Email this article New Fluorescent Reporter Systems for Evaluation of the Expression of E- and N-Cadherins
- Authors: Burmistrova O.A.1, Nikulin S.V.1, Zakharova G.S.1, Fomicheva K.A.2, Alekseev B.Y.2, Shkurnikov M.Y.2
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Affiliations:
- BioClinicum Center
- P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation
- Issue: Vol 165, No 1 (2018)
- Pages: 88-93
- Section: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240011
- DOI: https://doi.org/10.1007/s10517-018-4106-x
- ID: 240011
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Abstract
During metastatic growth, cells of solid tumors undergo phenotypical changes related to epithelial-mesenchymal transition. Epithelial-mesenchymal transition is regarded as a potential target for prospective antitumor drugs. Fluorescent reporter systems for evaluation of the expression of markers of epithelial and mesenchymal status (E- and N-cadherins) were created. The described approaches can be used for creation of analogous reporter systems.
About the authors
O. A. Burmistrova
BioClinicum Center
Author for correspondence.
Email: o.burmistrova@bioclinicum.com
Russian Federation, Moscow
S. V. Nikulin
BioClinicum Center
Email: o.burmistrova@bioclinicum.com
Russian Federation, Moscow
G. S. Zakharova
BioClinicum Center
Email: o.burmistrova@bioclinicum.com
Russian Federation, Moscow
K. A. Fomicheva
P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation
Email: o.burmistrova@bioclinicum.com
Russian Federation, Moscow
B. Ya. Alekseev
P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation
Email: o.burmistrova@bioclinicum.com
Russian Federation, Moscow
M. Yu. Shkurnikov
P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation
Email: o.burmistrova@bioclinicum.com
Russian Federation, Moscow
