New Fluorescent Reporter Systems for Evaluation of the Expression of E- and N-Cadherins


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详细

During metastatic growth, cells of solid tumors undergo phenotypical changes related to epithelial-mesenchymal transition. Epithelial-mesenchymal transition is regarded as a potential target for prospective antitumor drugs. Fluorescent reporter systems for evaluation of the expression of markers of epithelial and mesenchymal status (E- and N-cadherins) were created. The described approaches can be used for creation of analogous reporter systems.

作者简介

O. Burmistrova

BioClinicum Center

编辑信件的主要联系方式.
Email: o.burmistrova@bioclinicum.com
俄罗斯联邦, Moscow

S. Nikulin

BioClinicum Center

Email: o.burmistrova@bioclinicum.com
俄罗斯联邦, Moscow

G. Zakharova

BioClinicum Center

Email: o.burmistrova@bioclinicum.com
俄罗斯联邦, Moscow

K. Fomicheva

P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation

Email: o.burmistrova@bioclinicum.com
俄罗斯联邦, Moscow

B. Alekseev

P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation

Email: o.burmistrova@bioclinicum.com
俄罗斯联邦, Moscow

M. Shkurnikov

P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation

Email: o.burmistrova@bioclinicum.com
俄罗斯联邦, Moscow


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