New Fluorescent Reporter Systems for Evaluation of the Expression of E- and N-Cadherins
- Autores: Burmistrova O.1, Nikulin S.1, Zakharova G.1, Fomicheva K.2, Alekseev B.2, Shkurnikov M.2
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Afiliações:
- BioClinicum Center
- P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation
- Edição: Volume 165, Nº 1 (2018)
- Páginas: 88-93
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240011
- DOI: https://doi.org/10.1007/s10517-018-4106-x
- ID: 240011
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Resumo
During metastatic growth, cells of solid tumors undergo phenotypical changes related to epithelial-mesenchymal transition. Epithelial-mesenchymal transition is regarded as a potential target for prospective antitumor drugs. Fluorescent reporter systems for evaluation of the expression of markers of epithelial and mesenchymal status (E- and N-cadherins) were created. The described approaches can be used for creation of analogous reporter systems.
Sobre autores
O. Burmistrova
BioClinicum Center
Autor responsável pela correspondência
Email: o.burmistrova@bioclinicum.com
Rússia, Moscow
S. Nikulin
BioClinicum Center
Email: o.burmistrova@bioclinicum.com
Rússia, Moscow
G. Zakharova
BioClinicum Center
Email: o.burmistrova@bioclinicum.com
Rússia, Moscow
K. Fomicheva
P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation
Email: o.burmistrova@bioclinicum.com
Rússia, Moscow
B. Alekseev
P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation
Email: o.burmistrova@bioclinicum.com
Rússia, Moscow
M. Shkurnikov
P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation
Email: o.burmistrova@bioclinicum.com
Rússia, Moscow