New Fluorescent Reporter Systems for Evaluation of the Expression of E- and N-Cadherins


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Resumo

During metastatic growth, cells of solid tumors undergo phenotypical changes related to epithelial-mesenchymal transition. Epithelial-mesenchymal transition is regarded as a potential target for prospective antitumor drugs. Fluorescent reporter systems for evaluation of the expression of markers of epithelial and mesenchymal status (E- and N-cadherins) were created. The described approaches can be used for creation of analogous reporter systems.

Sobre autores

O. Burmistrova

BioClinicum Center

Autor responsável pela correspondência
Email: o.burmistrova@bioclinicum.com
Rússia, Moscow

S. Nikulin

BioClinicum Center

Email: o.burmistrova@bioclinicum.com
Rússia, Moscow

G. Zakharova

BioClinicum Center

Email: o.burmistrova@bioclinicum.com
Rússia, Moscow

K. Fomicheva

P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation

Email: o.burmistrova@bioclinicum.com
Rússia, Moscow

B. Alekseev

P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation

Email: o.burmistrova@bioclinicum.com
Rússia, Moscow

M. Shkurnikov

P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation

Email: o.burmistrova@bioclinicum.com
Rússia, Moscow


Declaração de direitos autorais © Springer Science+Business Media, LLC, part of Springer Nature, 2018

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