New Fluorescent Reporter Systems for Evaluation of the Expression of E- and N-Cadherins
- Авторы: Burmistrova O.1, Nikulin S.1, Zakharova G.1, Fomicheva K.2, Alekseev B.2, Shkurnikov M.2
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Учреждения:
- BioClinicum Center
- P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation
- Выпуск: Том 165, № 1 (2018)
- Страницы: 88-93
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240011
- DOI: https://doi.org/10.1007/s10517-018-4106-x
- ID: 240011
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Аннотация
During metastatic growth, cells of solid tumors undergo phenotypical changes related to epithelial-mesenchymal transition. Epithelial-mesenchymal transition is regarded as a potential target for prospective antitumor drugs. Fluorescent reporter systems for evaluation of the expression of markers of epithelial and mesenchymal status (E- and N-cadherins) were created. The described approaches can be used for creation of analogous reporter systems.
Об авторах
O. Burmistrova
BioClinicum Center
Автор, ответственный за переписку.
Email: o.burmistrova@bioclinicum.com
Россия, Moscow
S. Nikulin
BioClinicum Center
Email: o.burmistrova@bioclinicum.com
Россия, Moscow
G. Zakharova
BioClinicum Center
Email: o.burmistrova@bioclinicum.com
Россия, Moscow
K. Fomicheva
P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation
Email: o.burmistrova@bioclinicum.com
Россия, Moscow
B. Alekseev
P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation
Email: o.burmistrova@bioclinicum.com
Россия, Moscow
M. Shkurnikov
P. A. Hertsen Moscow Oncology Research Center, Branch of National Medical Research Radiology Center of the Ministry of Health of the Russian Federation
Email: o.burmistrova@bioclinicum.com
Россия, Moscow