The Role of Erythrocyte Receptors in Regulation of the Conformation and Distribution of Hemoglobin

G. V. Maksimov; O. V. Slatinskaya; E. S. Tkhor; N. A. Anisimov; S. N. Mamaeva; V. V. Shutova

doi:10.1134/S0006350919010123

The Role of Erythrocyte Receptors in Regulation of the Conformation and Distribution of Hemoglobin

Авторы: Maksimov G.V.¹, Slatinskaya O.V.¹, Tkhor E.S.¹, Anisimov N.A.², Mamaeva S.N.³, Shutova V.V.⁴
Учреждения:
1. Moscow State University
2. National Scientific Center Institute of Biomedical Problems
3. Ammosov Northeastern Federal University
4. Ogarev National Research Mordovia State University
Выпуск: Том 64, № 1 (2019)
Страницы: 57-61
Раздел: Cell Biophysics
URL: https://journals.rcsi.science/0006-3509/article/view/152847
DOI: https://doi.org/10.1134/S0006350919010123
ID: 152847

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Abstract—Using Raman spectroscopy, atomic force microscopy, and laser interferometry we found that variations in insulin-like growth factor (IGF-1) and purinergic compounds such as ATP in the blood influence the hemoglobin distribution and hematoporhyrin conformation in hemoglobin in erythrocytes. Our results suggest that receptor activation promotes changes in conformation of cytoskeletal protein molecules and hemoglobin.