Email this article The Role of Erythrocyte Receptors in Regulation of the Conformation and Distribution of Hemoglobin
- Authors: Maksimov G.V.1, Slatinskaya O.V.1, Tkhor E.S.1, Anisimov N.A.2, Mamaeva S.N.3, Shutova V.V.4
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Affiliations:
- Moscow State University
- National Scientific Center Institute of Biomedical Problems
- Ammosov Northeastern Federal University
- Ogarev National Research Mordovia State University
- Issue: Vol 64, No 1 (2019)
- Pages: 57-61
- Section: Cell Biophysics
- URL: https://journals.rcsi.science/0006-3509/article/view/152847
- DOI: https://doi.org/10.1134/S0006350919010123
- ID: 152847
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Abstract
Abstract—Using Raman spectroscopy, atomic force microscopy, and laser interferometry we found that variations in insulin-like growth factor (IGF-1) and purinergic compounds such as ATP in the blood influence the hemoglobin distribution and hematoporhyrin conformation in hemoglobin in erythrocytes. Our results suggest that receptor activation promotes changes in conformation of cytoskeletal protein molecules and hemoglobin.
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About the authors
G. V. Maksimov
Moscow State University
Author for correspondence.
Email: gmaksimov@mail.ru
Russian Federation, Moscow, 119892
O. V. Slatinskaya
Moscow State University
Email: gmaksimov@mail.ru
Russian Federation, Moscow, 119892
E. S. Tkhor
Moscow State University
Email: gmaksimov@mail.ru
Russian Federation, Moscow, 119892
N. A. Anisimov
National Scientific Center Institute of Biomedical Problems
Email: gmaksimov@mail.ru
Russian Federation, Moscow, 123007
S. N. Mamaeva
Ammosov Northeastern Federal University
Email: gmaksimov@mail.ru
Russian Federation, Yakutsk, Republic of Sakha (Yakutia), 677000
V. V. Shutova
Ogarev National Research Mordovia State University
Email: gmaksimov@mail.ru
Russian Federation, Saransk, Republic of Mordovia, 430005
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