Cicatricial complications of respiratory papillomatosis surgical treatment at the department of Saint Petersburg State Pediatric Medical University clinical hospital in 2019–2021
- Authors: Dmitrenko V.V.1, Pavlov P.V.1, Verezgov V.A.1, Zakharova M.L.1, Breusenko D.V.1, Kuryanova Y.A.1, Kukushkina O.E.1, Gorkina O.K.1
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Affiliations:
- Saint Petersburg State Pediatric Medical University
- Issue: Vol 14, No 4 (2023)
- Pages: 43-50
- Section: Original studies
- URL: https://journals.rcsi.science/pediatr/article/view/232067
- DOI: https://doi.org/10.17816/PED14443-50
- ID: 232067
Cite item
Abstract
BACKGROUND: Respiratory papillomatosis requires combined treatment, adjuvant therapy and surgical treatment. Scarring complications often occur after surgical treatment.
AIM: To determine the frequency of cicatricial complications of surgical treatment of respiratory papillomatosis in children.
MATERIALS AND METHODS: A retrospective analysis of the medical histories of 49 children who received surgical treatment at the clinic of the Saint Petersburg State Pediatric Medical University for 3 years (from 2019 to 2021) was carried out. The data obtained were compared with the data of a meta-analysis conducted in 2022.
RESULTS: In the otolaryngological department of Saint Petersburg State Medical University from 2019 to 2021, 49 children aged 1 to 17 years — 25 boys and 24 girls — received surgical treatment. Primary papillomatosis was detected in 9 patients. The first surgical intervention was at the age of 2 years in 12 children (24.5%). Combined treatment was used: endolaryngeal removal of laryngeal papillomas with microsurgical instruments and administration of interferon alpha-2b in the postoperative period. Of the 49 patients, scarring was detected in 16 (32.6%). However, 29 patients were operated only at the Saint Petersburg State Medical University clinic — the percentage of cicatricial complications among them was 20.6%. 20 patients turned to the Saint Petersburg State Medical University clinic after treatment in other institutions — the percentage of cicatricial complications among them was 50%. Of all 49 children examined, scarring occurred in the vocal region in 10 children (62.5%), in the larynx — in 2 children (12.5%), in both departments in 4 children (25%). Scarring changes were not detected in the sub-vocal part of the larynx. The number of operations per year for each child ranged from 1 to 7, and for 3 years (from 2019 to 2021), the number of operations reached 20.
CONCLUSIONS: Scarring complications after surgical treatment of respiratory papillomatosis are quite common. It was revealed that the first surgical treatment is more often in the first 3 years of life. The choice of surgical technique affects the frequency of cicatricial complications, however, it is extremely difficult to avoid cicatricial complications as long as there is a need for surgical treatment.
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##article.viewOnOriginalSite##About the authors
Valery V. Dmitrenko
Saint Petersburg State Pediatric Medical University
Author for correspondence.
Email: dmitrenko1411@mail.ru
ORCID iD: 0000-0003-2766-6577
Otorhinolaryngologist, Department of Otorhinolaryngology
Russian Federation, Saint PetersburgPavel V. Pavlov
Saint Petersburg State Pediatric Medical University
Email: pvpavlov@mail.ru
ORCID iD: 0000-0002-4626-201X
MD, PhD, Dr. Sci. (Med.), Assistant Professor, Head of the Department of Otorhinolaryngology
Russian Federation, Saint PetersburgVyacheslav A. Verezgov
Saint Petersburg State Pediatric Medical University
Email: verezgov@gmail.com
ORCID iD: 0000-0001-5049-916X
MD, PhD, Cand. Sci. (Med.), Otorhinolaryngologist, Department of Otorhinolaryngology
Russian Federation, Saint PetersburgMaria L. Zakharova
Saint Petersburg State Pediatric Medical University
Email: dr.essina@mail.ru
ORCID iD: 0000-0001-6410-3533
MD, PhD, Dr. Sci. (Med.), Assistant Professor of the Department of Otorhinolaryngology
Russian Federation, Saint PetersburgDmitry V. Breusenko
Saint Petersburg State Pediatric Medical University
Email: lor-gpma@mail.ru
ORCID iD: 0000-0003-2983-4124
MD, PhD, Cand. Sci. (Med.), Head of the Department of Otorhinolaryngology
Russian Federation, Saint PetersburgYulia A. Kuryanova
Saint Petersburg State Pediatric Medical University
Email: Julia_ku@mail.ru
ORCID iD: 0000-0003-3843-0201
Otorhinolaryngologist, Department of Otorhinolaryngology
Russian Federation, Saint PetersburgOlga E. Kukushkina
Saint Petersburg State Pediatric Medical University
Email: o.lka@mail.ru
ORCID iD: 0000-0001-5351-3764
Otorhinolaryngologist, Department of Otorhinolaryngology
Russian Federation, Saint PetersburgOksana K. Gorkina
Saint Petersburg State Pediatric Medical University
Email: gorkina-ok@yandex.ru
ORCID iD: 0000-0002-2527-9023
Assistant of the Department Otorhinolaryngology
Russian Federation, Saint PetersburgReferences
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