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发表评论 Morphological study of idiopathic epiretinal membranes and their cytokine profile
- 作者: Altynbaev U.1, Lebedeva A.2
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隶属关系:
- OAO “Tatneft”
- Federal State Institution “All-Russian Eye and Plastic Surgery Center”
- 期: 卷 9, 编号 4 (2016)
- 页面: 13-17
- 栏目: Articles
- URL: https://journals.rcsi.science/ov/article/view/6004
- DOI: https://doi.org/10.17816/OV9413-17
- ID: 6004
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详细
The article presents comparative morphological analysis and assessment of response to antigens of fibronectin, laminin, glial fibrillary acidic protein (GFAP) in idiopathic epiretinal membranes (iERM). Authors found a comparable positive iERM reaction to fibronectin and GFAP, which indicates the involvement of these cytokines in the development and progression of the posterior segment neurodegenerative process. Cellular elements in the vitreous gel responsible for iERM formation were fibroblasts, myofibroblasts, hyalocytes, and retinal radial glial cells. Retinal radial glial cells play the main role in the recurrent iERM formation.
Conclusion. Due to its hemodynamic, nootropic, neurotrophic action, the investigated bioregulatory complex increases the optic nerve tolerance to the stress effect of IOP, SBP, and DBP asynchronous fluctuations, and improves the ocular blood perfusion.
作者简介
Ural Altynbaev
OAO “Tatneft”
编辑信件的主要联系方式.
Email: uralaltynbaev@rambler.ru
MD, PhD. Ophthalmology Department, Medical Unit 俄罗斯联邦
Anna Lebedeva
Federal State Institution “All-Russian Eye and Plastic Surgery Center”
Email: morpholetter@yandex.ru
PhD, head of histology and immunohistochemistry laboratory. Morphology Department 俄罗斯联邦
参考
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