Ophthalmology Journal

Medical peer-reviewed quarterly journal published since 2008.

Chief editor

professor Dmitriy V. Davydov, MD, Ph.D.
ORCID: 0000-0001-5506-6021 

About

Main publications of the journal are focused on key issues of modern ophthalmology: etiology and pathogenesis, epidemiology, clinical picture features, up-to-date methods of diagnosis, prevention, and treatment of eye diseases and of those of its adnexa.

The journal publishes original articles, scientific reviews, lectures, clinical case descriptions (presented by Russian and foreign authors), and informs about past congresses and conferences in Russia.

The journal is oriented toward practicing ophthalmologists, including ophthalmic surgeons, scientific and teaching staff of medical higher educational institutions, physicians in ophthalmology training, as well as for specialists of allied health specialties.

The journal’s mission:

  1. To integrate research results of Russian scientists and the rich clinical experience of practicing doctors in diagnosis, prevention, and treatment of eye diseases into the international scientific space; to be an international scientific platform for discussions and sharing experiences;
  2. To provide for ophthalmologists of the Russian Federation actual and high quality research and practice insights into most up-to-date treatment and prevention methods of eye diseases and of those of its adnexa.

Publications

  • in English, Russian, Chinese 
  • in hybrid access (subscription and Open Access with СС BY license)
  • with no APC for all authors

Indexation

  • RSCI (Web of Science)
  • eLibrary.ru
  • Google Scholar
  • Ulrich's Periodicals Directory
  • WorldCat
  • CNKI
  • Publons

The journal is registered by the Russian State Committee for Press and Mass Media on May 04, 2016 (Registration Number ПИ № ФС 77-65574).

Current Issue

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Vol 17, No 4 (2024)

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Original researches

Features of visual field changes in patients with degenerative optic neuropathies
Simakova I.L., Kulikov A.N., Tikhonovskaya I.A.
Abstract

BACKGROUND: Degenerative optic neuropathies are one of the leading causes of irreversible blindness. The most accessible and effective methods of their early diagnosis are standard and non-standard perimetry.

AIM: The aim of this study is to identify the features of visual field changes in patients with degenerative optic neuropathies.

MATERIALS AND METHODS: The study involved 56 patients (97 eyes) with degenerative optic neuropathies, divided into 3 groups, and the control group consisted of 60 healthy individuals (60 eyes). In addition to the standard ophthalmological examination, all subjects underwent Humphrey visual field testing and Frequency Doubling Technology (FDT) perimetry in the author’s modification.

RESULTS: In patients with degenerative optic neuropathies, the sensitivity level of both FDT perimetry strategies turned out to be significantly higher in the detection of primary open-angle glaucoma than in that of multiple sclerosis, and the specificity level was 2 times higher than that of the Humphrey visual field testing. The data of the variance analysis showed that the results of FDT perimetry reliably separate patients with degenerative optic neuropathies from healthy individuals, but it is not always possible to determine the type of optic neuropathy.

CONCLUSIONS: Both threshold strategies of FDT perimetry are more effective in detecting optic neuropathy in primary open-angle glaucoma than in multiple sclerosis in terms of sensitivity. They have higher specificity than Humphrey perimetry, which indicates the advantage of FDT perimetry in separation between healthy people and patients with degenerative optic neuropathies, and not only of glaucomatous nature. The moderate and reliable correlation between the MD indices of all three strategies of perimetry indicates the expediency of their integrated use for early diagnosis of primary open-angle glaucoma.

Ophthalmology Journal. 2024;17(4):7-19
pages 7-19 views
YAG-laser treatment of secondary cataract with silicone tamponade of the vitreous cavity
Ratanova P.S., Kleimenov A.Y., Zykov O.A., Shuman N.S., Arapova A.D., Strenev N.V.
Abstract

BACKGROUND: Silicone tamponade of the vitreous cavity can be indefinitely long due to severe forms of diabetic retinopathy, recurrent hemophthalmos, and recurrent retinal detachment. Prolonged contact of the capsular bag with tamponade agent leads to posterior capsule fibrosis and cataract development, including secondary cataract in pseudophakia, which significantly reduces the visual outcome of surgery. The technique of laser posterior capsulotomy has some peculiarities related to the tight contact of the posterior capsule with the silicone oil. Often the procedure cannot be completed successfully, and surgical dissection of the secondary cataract has to be performed. Repeated surgical procedure also has certain complexities and becomes even more risky, as there is an increased risk of IOL damage, IOL dislocation, and migration of silicone oil into the anterior chamber, which does not allow to improve the functional outcome of the intervention.

AIM: The aim of this study is to develop and present the own modified technique of YAG-laser posterior capsulotomy in eyes after vitrectomy with long-term silicone oil tamponade.

MATERIALS AND METHODS: This study presents the results of treatment of 12 patients (12 eyes), including 2 women and 10 men (16.67% and 83.33%), age from 16 to 60 (42.83 ± 7.89) years with prolonged “light” silicone oil tamponade and secondary cataract. Posterior capsulotomy was performed with YAG-laser using the developed technology. Best-corrected visual acuity before surgery ranged from 0.01 to 0.2 (0.07 ± 0.01), intraocular pressure before surgery ranged from 7 to 20 (11.83 ± 2.21) mm Hg. The term of silicone tamponade was from 4 to 51 (24 ± 6.48) months. The follow-up time for patients operated using this technology ranged from 1 to 60 (27.33 ± 9.95) days.

RESULTS: As a result of treatment, the dissection of the posterior lens capsule was achieved in 12 out of 12 patients (100%). No intraoperative and postoperative complications were observed. Postoperative best-corrected visual acuity ranged from 0.05 to 0.3 (0.13 ± 0.02), and intraocular pressure from 7 to 22 (13 ± 2.37) mm Hg. In all cases, the diameter of the optical area was sufficient and amounted to 3–4 mm, the flap of the posterior capsule was completely separated as a whole fragment.

CONCLUSIONS: The developed method of modified YAG-laser posterior capsulotomy (Patent RU No. 2782725, priority from December 27, 2021) in eyes with a long term silicone oil tamponade is effective and can be used in everyday medical practice. The advantages of the proposed method: high efficacy when performing the procedure in a complex category of patients with no additional procedures required. The procedure is a modification of a routine technology, and does not require additional equipment and training.

Ophthalmology Journal. 2024;17(4):21-28
pages 21-28 views
Analysis of the surgical treatment results of large idiopathic macular holes using tamponade with internal limiting membrane flaps and platelet-rich plasma
Shchukin A.D., Veryasova A.G., Gnatyuk Y.V., Smirnov O.B.
Abstract

BACKGROUND: Penetrating macular holes of the retina remain today one of the main reasons for a significant loss of central vision, especially in working age patients. At the same time, the mainstream problem are the validity and effectiveness of treatment of large and giant macular holes with a diameter of more than 500–1000 µm.

AIM: to optimize the treatment method for patients with large and long-standing macular holes. To analyze the results of treatment of patients with this condition.

MATERIALS AND METHODS: In 2023, 56 patients were operated on for idiopathic large macular hole. During vitrectomy, a new surgical technique was used for the macular hole bed tamponade with flaps of the internal limiting membrane in combination with the introduction of platelet-rich plasma.

RESULTS: After the resorption of the gas-air mixture (1–1.5 months after surgery), ophthalmoscopically and according to optical coherence tomography data, closure of the macular hole was observed in 51 of 56 operated patients, which amounted to 91.1%.

CONCLUSIONS: The surgical treatment technique used allows for closure of large macular holes in 91.1%.

Ophthalmology Journal. 2024;17(4):29-36
pages 29-36 views
Method of intraocular lens fixation in patients with compensated glaucoma and cataract complicated by zonular weakness
Ivachev E.A., Kochergin S.A., Ivacheva O.T.
Abstract

BACKGROUND: The combination of cataract and glaucoma occurs in 14.6–76% of cases, and zonular weakness — in 34%. By suturing the lens in the posterior chamber, ophthalmic surgeons create a more physiological position for it.

AIM: The aim of this study is to evaluate the clinical efficacy of intraocular lens fixation in patients with compensated glaucoma and cataract complicated by zonular weakness.

MATERIALS AND METHODS: 49 patients with compensated glaucoma and cataract complicated by zonular weakness were operated. Uncorrected visual acuity — 0.19, best corrected visual acuity — 0.25, tonometric intraocular pressure — 18.9 mm Hg. Operation technique: a corneal tunnel is formed at 9 o’clock, 4 iris-retractors are inserted through paracenteses at 2, 5, 8, 11 hours and fixed at the edge of the capsulorhexis. After lens extraction, 2 iris-retractors (at 5, 11 hours) are removed . The lens is implanted into the anterior chamber. Haptic elements are tucked under the iris in the projection of 5 and 11 hours, the optical part is transferred to the posterior chamber. The support elements are sutured with interrupted sutures to the iris, then 2 iris-retractors are removed (at 2 and 8 hours), the capsular bag is removed using tweezers, and the paracenteses and the tunnel are hydrated.

RESULTS: On the first day, the best corrected visual acuity was 0.34, by the 5th day, it increased to 0.49 ± 0.08, by the 14th day — 0.52. As the glaucoma process progressed during 2 years after surgery, best corrected visual acuity decreased to 0.47, intraocular pressure was 18.4 mm Hg.

CONCLUSIONS: An original and easy to perform suture fixation of the lens to the iris is proposed, which allows to reduce the risk of lens decentration and tilt, as well as that of vitreous herniation.

Ophthalmology Journal. 2024;17(4):37-44
pages 37-44 views
Anonymous survey results of ophthalmology residents of Russian medical universities on the status of their visual analyzer
Avkhadeeva S.R., Antonyan V.B., Aprelev A.E., Astakhov S.Y., Beldovskaya N.Y., Bobykin E.V., Gavrilova T.V., Drozdova E.A., Zagidullina A.S., Zumbulidze N.G., Ismailova S.B., Kamenskikh T.G., Kovalevskaya M.A., Korotkikh S.A., Krokhalev V.Y., Lebedev O.I., Martusevich Y.A., Medvedev I.B., Nechiporenko P.A., Pozdnyakova P.N., Pokrovskii D.F., Ponomareva M.N., Solovyeva L.I., Surov A.V., Tur E.V., Filina L.A., Fursova A.Z., Chistyakova S.V.
Abstract

BACKGROUND: A widespread visual impairment among medical students is known, but there are no data on the ophthalmic status of clinical residents.

AIM: To carry out an assessment of the visual analyzer status in Russian medical universities graduates who begin the clinical residency according to the specialty 31.08.59 Ophthalmology.

MATERIALS AND METHODS: An anonymous residents’ online survey was conducted in 15 universities from 14 cities using an original interactive questionnaire. Responses were received from 249 respondents (mostly females: n = 188, 75.5%; mean age 24.80 ± 0.06 years). To compare, we used previously published data on a survey of senior students from 5 Russian medical universities, including 549 respondents (425 females, 77.4%; mean age 22.4 ± 0.06 years).

RESULTS: In comparison to students, residents were significantly more likely to rate their vision as excellent (20.8% and 28.9%, respectively, p = 0.01), to report emmetropia (16.2% versus 26.9%, p < 0.001), to deny continuing vision deterioration (33.0% and 43.5%, p < 0.005), to rate higher the importance of good vision (9.25 ± 0.06 and 9.73 ± 0.05 conditional points, respectively, p < 0.01). Students significantly more often did not know the meaning of the “clinical refraction” term (2.6% and 0.4%, respectively, p = 0.04), more often reported vision problems interfering with their studies (26.2% and 15.7%, p = 0.01), and reported ongoing vision deterioration (57.9% versus 45.0%, p < 0.001). Otherwise, survey results were comparable.

CONCLUSIONS: Visual impairments are widespread among clinical residents-ophthalmologists of Russian medical universities, 58.2% of the responders had ametropia (including 56.1% of myopia), 28.5% had astigmatism, 3.6% had other ocular conditions. The majority of survey participants (59.8%) used or felt a need in optical correction, 19.7% rated their vision as “poor” or “very poor”, about a half (45.0%) believed their vision to worsen during recent years, and about as much (46.6%) reported that they experience limitations in everyday life related to decreased vision. Insufficient awareness of a part of the responders about their vision, and in some responders, a lack in basic ophthalmological knowledge were revealed.

Ophthalmology Journal. 2024;17(4):45-56
pages 45-56 views
Using equivalent keratometric readings in calculating the optical power of a multifocal intraocular lens
Boiko E.V., Petrosyan Y.M., Shukhaev S.V., Molodkin A.V.
Abstract

BACKGROUND: Modern keratotopography allows calculating Equivalent Keratometer Readings (EKR), which take additionally into account in keratometry the radius of curvature of corneal posterior surface, and this could lead to more accurate calculation of the spherical equivalent (SE) of the intraocular lens.

AIM: The aim of this study is to determine the accuracy of calculating the SE of multifocal intraocular lens according to EKR data, depending on the formula used and the corneal zone.

MATERIALS AND METHOD: The study included 78 patients who underwent femtolaser-assisted phacoemulsification, multifocal intraocular lens implantation and achievement of the target refraction at different distances. Retrospective calculation of the optical power of the intraocular lens was performed using biometric data from OA-2000 and EKR (zones from 0.5 to 5 mm in increments of 0.5 mm) using 10 formulas (SRK/T, Holladay 1, Holladay 2, Haigis, Hoffer Q, Barrett 2 Universal, Olsen, Kane, EVO, Hill RBF). For each combination of keratometry zone/formula were calculated: mean error of predicted refraction (ME), its difference from zero, and after intraocular lens constant optimization — mean (MAE) and median (MedAE) absolute errors, standard deviation (SD).

RESULTS: Up to the 2.5 mm zone, ME is shifted towards hypermetropia, and from the 3 mm zone, ME begins to shift towards myopia according to all formulas. Minimal MAE, MedAE and SD values were detected in peripheral corneal zones (3–5 mm) for most formulas. The best indicators were demonstrated by the formula Haigis in zones 3.5–5 mm.

CONCLUSIONS: The most accurate calculation of the SE of a multifocal intraocular lens using EKR is possible when using the Haigis formula in 3.5–5 mm zones.

Ophthalmology Journal. 2024;17(4):57-65
pages 57-65 views
Implantation of Ahmed drainage device in secondary “silicone” glaucoma. Features of the postoperative course
Starostina A.V., Sidorova A.V., Uyanaeva A.A., Sorokoletov G.V., Burlakov K.S.
Abstract

BACKGROUND: Despite the high technological effectiveness of treatment methods for vitreoretinal conditions, secondary glaucoma is a fairly common complication in the postoperative period, especially after tamponade with silicone oil.

AIM: The aim of this study is to evaluate the effectiveness of Ahmed valve drainage device implantation in secondary glaucoma after vitreoretinal surgery with silicone oil tamponade and after the silicone oil removal.

MATERIALS AND METHODS: The study included 42 patients with secondary glaucoma after vitreoretinal procedures with silicone oil tamponade for rhegmatogenous retinal detachment. Patients were divided into two groups: group 1 included 27 patients with avitria after silicone oil removal, group 2 — 15 patients with silicone oil tamponade in whom silicone oil removal was not indicated for various reasons. Before surgery, decompensation of intraocular pressure was detected in all patients (32.5 ± 2.9 mmHg, at the maximum hypotensive regimen), visual acuity varied from counting fingers to 0.5 with no correction of refractive error possible.

RESULTS: In all cases, anti-glaucoma surgeries with Ahmed valve implantation were performed without complications. In the early postoperative period, the hypotensive effect was achieved in 100% of cases in both groups, the level of intraocular pressure on the first day after surgery in patients with avitria after removal of silicone oil averaged 9.3 ± 1.5 mmHg, in the group with silicone oil in the vitreal cavity — 10.2 ± 1.8 mmHg. The most common complication in the early postoperative period in patients with silicone oil tamponade was a shallow anterior chamber (in 40% of cases). Intraocular pressure was compensated in all patients within 12 months.

CONCLUSIONS: The use of Ahmed drainage device is an effective method of intraocular pressure normalization in patients with secondary glaucoma after vitreoretinal procedures, both with silicone oil tamponade and avitria.

Ophthalmology Journal. 2024;17(4):67-75
pages 67-75 views

In ophthalmology practitioners

Comparative analysis of clinical and functional results of sublamellar keratoablation using solid-state and excimer laser devices
Maychuk N.V., Tikhov A.V., Takhchidi K.P., Sarkhadov N.S., Malyshev I.S.
Abstract

BACKGROUND: The most popular method of keratorefractive surgery is sublamellar valve technology. It is known that excimer laser systems, which are widely used and are the gold standard in keratorefractive surgery, have a number of disadvantages. Alternative sources of UV radiation generation are solid-state laser systems, in particular the domestic Olimp 2000/213 laser, which previously had no experience in femto-assisted sublamellar surgery.

AIM: To evaluate clinical and functional results of correction of mild, moderate and high myopia using sublamellar keratomileusis technology, performed using the Schwind Amaris 1050 rs excimer laser and the Olimp 2000/213 solid-state ablative laser.

MATERIALS AND METHODS: 190 patients (190 eyes) with stationary myopia were examined and operated on. The follow-up period was 1 year after surgery. The main group consisted of patients who underwent myopia correction using sublamellar keratoablation technology using a solid-state laser Olimp 2000/213 — 92 eyes. The control group consisted of patients after FemtoLASIK, in whom ablation was performed using a Schwind Amaris 1050 rs laser (98 eyes). A comparative analysis was carried out according to modern criteria for refractive surgery.

RESULTS: 190 patients (190 eyes) with stationary myopia were examined and operated on. The follow-up period was 1 year after surgery. The main group patients underwent myopia correction using sublamellar keratoablation technology using a solid-state laser Olimp 2000/213 — 92 eyes. The control group consisted of patients after FemtoLASIK correction, in whom ablation was performed using a Schwind Amaris 1050 rs laser (98 eyes). A comparative analysis was carried out according to modern criteria for refractive surgery.

CONCLUSIONS: The analysis of the clinical and functional results of myopia correction using the technology of sublamellar keratoablation, performed using the Olimp 2000/213 solid-state ablative laser and the Schwind Amaris 1050 rs excimer laser, showed a high comparability of the technologies.

Ophthalmology Journal. 2024;17(4):77-86
pages 77-86 views

Case reports

Toric to monofocal intraocular lens exchange in patient with subepithelial fibroplasia after radial keratotomy. Clinical case
Malyugin B.E., Kalinnikova S.Y., Tkachenko I.S., Khaletskaya A.A., Melovatskiy P.D.
Abstract

This clinical case demonstrates the toric to monofocal intraocular lens exchange due to the erroneous assessment of corneal topography in a patient with radial corneal scars after keratotomy. Toric intraocular lens power calculation was performed using initial parameters, when its central optical area was transparent, and at the mid-periphery, approximately 4–5 mm from the central optical area in the upper temporal quadrant, there was a subepithelial fibroplasia present. Postoperative refractive result was not optimal; residual astigmatism was noted, and it was decided to eliminate it by scarification of the epithelium in the area of fibroplasia. This lead to a significant change in keratometry and to practically total restoration of corneal spherical form. IOL exchange was performed, which caused an increase in visual function.

Ophthalmology Journal. 2024;17(4):87-98
pages 87-98 views

Reviews

Eye microcirculation in glaucoma. Part 2. Disorders of regional hemodynamics
Petrov S.Y., Orlova E.N., Kiseleva T.N., Okhotsimskaya T.D., Markelova O.I.
Abstract

Glaucoma is one of the leading causes of blindness worldwide. The etiology of primary glaucoma is usually divided into mechanical and vascular mechanisms. Research of the vascular component of glaucoma was going on since the beginning of the last century with continuous improvement of diagnostic methods from invasive to high-tech non-contact ones. Modern and promising methods are: ultrasound examination in color Doppler mapping and pulsed Doppler modes, optical coherence tomography angiography, and laser speckle flowgraphy. The review describes specific for glaucoma blood flow changes in ocular vessels, correlating with functional and structural changes: decrease of vascular density in macular, parafoveolar, and peripapillary areas, decrease of the integral indicator of microcirculation, decrease of the indicators of volume and linear blood flow velocities in retinal and choroidal vessels, impaired retrobulbar blood circulation. The analysis of literature data is presented concerning the investigation of hemodynamic disturbances in ocular vessels in normotensive glaucoma and glaucoma in myopic eyes, in systemic blood flow disturbances (arterial hypertension and hypotension) in patients with glaucomatous optic neuropathy.

Ophthalmology Journal. 2024;17(4):99-110
pages 99-110 views
Prospects of minimally invasive surgery in the treatment of primary open-angle glaucoma
Minnigaliev V.M., Khamadullina N.A., Gonchar M.I., Ekhtangirova D.K., Sozaeva F.M., Shirukova A.M., Alhajali H., Cherkesova Z.M., Karakizova L.M., Ibragimova U.A., Kerimova M.Z.
Abstract

The article examines the prospects of minimally invasive glaucoma surgery in the treatment of primary open-angle glaucoma. The primary focus is on the effectiveness and safety of contemporary minimally invasive glaucoma surgery techniques, such as iStent, MicroShunt, and Hydrus. The authors highlight the significant reduction in intraocular pressure and the decrease in dependence on medication therapy for most patients following these procedures. The article presents results from numerous clinical studies demonstrating the high effectiveness and safety of these methods. The uniqueness of this review lies in the comprehensive analysis of current data and the identification of key advantages of minimally invasive glaucoma surgery compared to traditional glaucoma treatment methods. The article also emphasizes the economic feasibility of minimally invasive glaucoma surgery, which can significantly reduce the burden on healthcare systems in various regions. The authors point out the necessity for further research to evaluate the long-term effectiveness and safety of these technologies, as well as to determine optimal management strategies for primary open-angle glaucoma in different population subgroups. Detailed meta-analyses and multicenter studies could contribute to better understanding of the mechanisms of action and potential limitations of these technologies, providing a basis for personalized approach to glaucoma treatment.

Ophthalmology Journal. 2024;17(4):111-124
pages 111-124 views

Discussion

Cataract surgery: rational algorithm of postoperative examination of patients
Nikolaenko V.P., Belov D.F., Аntonova A.V.
Abstract

The article is devoted to the presentation of a rational algorithm of post-operative visits of patients who have undergone phacoemulsification. Uncomplicated phacoemulsification of senile cataract performed by an experienced surgeon allows giving up postoperative examinations at the clinic confining them to one visit to a polyclinic in the home area during two weeks after the procedure, but only if the two following preconditions are met. The first is the ability of the patient to promptly report any changes in his health and, if necessary, to arrive immediately for examination at the clinic. The second is effective pharmaceutical support for phacoemulsification, which is intended to solve two main tasks — prevention of infectious complications and control of inflammation.

Ophthalmology Journal. 2024;17(4):125-132
pages 125-132 views


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