常规抗血管生成治疗期间糖尿病性黄斑水肿的玻璃体视网膜交界面变化动态观察

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该项工作主要研究了初步诊断为糖尿病性黄斑水肿患者玻璃体视网膜交界面 (VRI) 的状态以及在常规雷珠单抗抗血管生成治疗期间的变化。初步诊断出 VRI 病变的检出率为 49.3%。在常规抗血管生成治疗的情况下,最初正常的 VRI 转变为病理性的VRI占 6%,最初病理性的 VRI 转变为正常或其他病理性的占 15.8%. 由于有不低于 7.9% 的情况病理性 VRI 有可能转变成正常,因此,最初的病理性 VRI 不是玻璃体切除术的绝对指征。

作者简介

Dzhambulat Oskanov

S.N. Fedorov NMRC “MNTK “Eye Microsurgery”

编辑信件的主要联系方式.
Email: oskanovd@mail.ru
ORCID iD: 0000-0001-8842-2643
SPIN 代码: 9853-5775

Ophthalmologist

俄罗斯联邦, Saint Petersburg

Sergei Sosnovskii

S.N. Fedorov NMRC “MNTK “Eye Microsurgery”

Email: svsosnovsky@mail.ru

Assistant-Professor, PhD, MD of Highest Qualification, Ophthalmologist

俄罗斯联邦, Saint Petersburg

Ernest Boiko

S.N. Fedorov NMRC “MNTK “Eye Microsurgery”; North-Western State Medical University named after I.I. Mechnikov; Military Medical Academy named after S.M. Kirov

Email: boiko111@list.ru

Professor, Doctor of Medical Science, Honored MD of Russian Federation, Director; Professor, Head, Ophthalmology Department

俄罗斯联邦, Saint Petersburg

Roman Berezin

S.N. Fedorov NMRC “MNTK “Eye Microsurgery”

Email: berrom@yandex.ru

PhD, Ophthalmologist

俄罗斯联邦, Saint Petersburg

Tat’yana Kotsur

S.N. Fedorov NMRC “MNTK “Eye Microsurgery”

Email: tatiana781@yandex.ru

MD, Ophthalmologist. Laser Microsurgery and Fluorescent Angiography Department

俄罗斯联邦, Saint Petersburg

参考

  1. Нероев В.В. Современные аспекты лечения диабетического макулярного отёка // Российский офтальмологический журнал. – 2012. – Т. 5. – № 1. – С. 4–7. [Neroev VV. Current issues in the treatment of diabetic macular edema. Rossiiskii oftal’mologicheskii zhurnal. 2012;5(1):4-7. (In Russ.)]
  2. Brown DM, Schmidt-Erfurth U, Do DV, et al. Intravitreal aflibercept for diabetic macular edema: 100-week results from the VISTA and VIVID studies. Ophthalmology. 2015;122(10):2044-2052. https://doi.org/10.1016/j.ophtha.2015.06.017.
  3. Zimmet P, Alberti KG, Shaw J. Global and societal implications of the diabetes epidemic. Nature. 2001;414(6865):782-787. https://doi.org/10.1038/414782a.
  4. Щуко А.Г. Оптическая когерентная томография в диагностике глазных болезней / Под ред. проф. А.Г. Щуко, проф. В.В. Малышева. – М.: ГЭОТАР-Медиа, 2010. – 128 с. [Shchuko AG. Opticheskaya kogerentnaya tomografiya v diagnostike glaznykh boleznei. Ed. by A.G. Shchuko, V.V. Malyshev. Moscow: GEOTAR-Media; 2010. 128 р. (In Russ.)]
  5. Бойко Э.В., Сосновский С.В., Березин Р.Д., и др. Антиангиогенная терапия в офтальмологии. – СПб.: ВМедА им. С.М. Кирова, 2013. – 292 с. [Boyko EV, Sosnovskiy SV, Berezin RD, et al. Antiangiogennaya terapiya v oftal’mologii. Saint Petersburg: S.M. Kirov Military Medical Academy; 2013. 292 р. (In Russ.)]
  6. Khan IA, Mohamed MD, Mann SS, et al. Prevalence of vitreomacular interface abnormalities on spectral domain optical coherence tomography of patients undergoing macular photocoagulation for centre involving diabetic macular oedema. Br J Ophthalmol. 2015;99(8): 1078-1081. https://doi.org/10.1136/bjophthalmol-2014-305966.
  7. Kozak I, Barteselli G, Sepah YJ, et al. Correlation of vitreomacular traction with foveal thickness, subfoveal choroidal thickness, and vitreomacular/foveal angle. Curr Eye Res. 2017;42(2):297-301. https://doi.org/10.1080/02713683.2016.1175020.
  8. Гацу М.В., Байбородов Я.В. Клинико-топографическая классификация диабетических макулопатий // Сахарный диабет. – 2008. – № 3. – С. 20–22. [Gatsu MV, Bayborodov YV. Kliniko-topograficheskaya klassifikatsiya diabeticheskikh makulopatii. Diabetes mellitus. 2008;(3):20-22. (In Russ.)]
  9. Шкворченко Д.О., Захаров В.Д., Русановская А.В. и др. Оптимизация тактики ведения пациентов с витреофовеолярным тракционным синдромом // Катарактальная и рефракционная хирургия. – 2014. – Т. 14. – № 3. – С. 23–27. [Shkvorchenko DO, Zakharov VD, Rusanovskaya AV, et al. Optimization clinical management vitreofoveolar traction syndrome. Kataraktal’naia i refraktsionnaia khirurgiia. 2014;14(3):23-27. (In Russ.)]
  10. Maier M, Abraham S, Frank C, et al. therapeutic options in vitreomacular traction with or without a macular hole. Klin Monbl Augenheilkd. 2016;233(5):622-630. https://doi.org/10.1055/s-0042-101349.
  11. Meuer SM, Myers CE, Klein BE, et al. The epidemiology of vitreoretinal interface abnormalities as detected by sd-oct: the beaver dam eye study. Ophthalmology. 2015;122(4):787-795. https://doi.org/10.1016/j.ophtha.2014.10.014.
  12. Sonmez K, Capone A, Trese MT, et al. Vitreomacular traction syndrome: impact of anatomical configuration on anatomical and visual outcomes. Retina. 2008;28(9):1207-1214. https://doi.org/10.1097/IAE.0b013e31817b6b0f.
  13. Duker JS, Kaiser PK, Binder S, et al. The International Vitreomacular Traction Study Group classification of vitreomacular adhesion, traction, and macular hole. Ophthalmology. 2013;120(12): 2611-2619. https://doi.org/10.1016/j.ophtha.2013.07.042.
  14. Kumagai K, Hangai M, Larson E, et al. Vitreoretinal interface and foveal deformation in asymptomatic fellow eyes of patients with unilateral macular holes. Ophthalmology. 2011;118(8): 1638-1644. https://doi.org/10.1016/j.ophtha.2011.01.022.
  15. Wong Y, Steel DH, Habib MS, et al. Vitreoretinal interface abnormalities in patients treated with ranibizumab for diabetic macular oedema. Graefes Arch Clin Exp Ophthalmol. 2017;255(4): 733-742. https://doi.org/10.1007/s00417-016-3562-0.
  16. Kulikov AN, Sosnovskii SV, Berezin RD, et al. Vitreoretinal interface abnormalities in diabetic macular edema and effectiveness of anti-VEGF therapy: an optical coherence tomography study. Clin Ophthalmol. 2017;11:1995-2002. https://doi.org/10.2147/OPTH.S146019.
  17. Ferrara N, Henzel WJ. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun. 1989;161(2):851-858. https://doi.org/10.1016/0006-291x(89)92678-8.
  18. Stewart MW. The expanding role of vascular endothelial growth factor inhibitors in ophthalmology. Mayo Clin Proc. 2012;87(1): 77-88. https://doi.org/10.1016/j.mayocp.2011.10.001.
  19. Шишкин М.М., Юлдашева Н.М., Антонюк С.В., и др. Дифференцированный подход к назначению ингибиторов ангиогенеза при диабетическом макулярном отёке // Вестник Национального медико-хирургического центра им. Н.И. Пирогова. – 2011. – Т. 6. – № 3. – С. 24–28. [Shishkin MM, Yuldasheva NM, Antonyuk SV, et al. A differentiated approach to the prescription of angiogenesis inhibitors for diabetic macular edema. National medical and surgical center named after N.I. Pirogov. 2011;6(3):24-28. (In Russ.)]
  20. Elman MJ, Aiello LP, Ferris FL, et al.; DRCRNet. Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology. 2010;117(6):1064-1077. https://doi.org/10.1016/j.ophtha.2010.02.031.
  21. Mitchell P, Bandello F, Schmidt-Erfurth U, et al. The restore study: ranibizumab monotherapy or combined with laser versus laser monotherapy for diabetic macular edema. Ophthalmology. 2011;118(4):615-625. https://doi.org/10.1016/j.ophtha. 2011.01.031.
  22. Yoon D, Rusu I, Barbazetto I. Reduced effect of anti-vascular endothelial growth factor agents on diabetics with vitreomacular interface abnormalities. Int Ophthalmol. 2014;34(4):817-823. https://doi.org/10.1007/s10792-013-9884-6.
  23. Abcouwer SF. Angiogenic factors and cytokines in diabetic retinopathy. J Clin Cell Immunol. 2013; Suppl 1(11):1-12. https://doi.org/10.4172/2155-9899.
  24. Pacella F, Ferraresi AF, Turchetti P, et al. Intravitreal injection of Оzurdex® implant in patients with persistent diabetic macular edema, with six-month follow-up. Ophthalmol Eye Dis. 2016;8:11-16. https://doi.org/10.4137/OED.S38028.
  25. Байбородов Я.В., Балашевич Л.И. Оптимизация техники витрэктомии при поздних стадиях пролиферативной диабетической ретинопатии // Сахарный диабет. – 2008. – № 3. – С. 16–19. [Bayborodov YV, Balashevich LI. Optimizatsiya tekhniki vitrektomii pri pozdnikh stadiyakh proliferativnoi diabeticheskoi retinopatii. Diabetes mellitus. 2008;(3):16-19. (In Russ.)]
  26. Chang CK, Cheng CK, Bai CH, et al. Development of vitreo macular interface abnormality in patients with diabetic macular edema. Taiwan J Ophthalmol. 2012;2(3):93-98. https://doi.org/10.1016/j.tjo.2012.05.001.
  27. Ophir A, Martinez MR, Mosqueda P, et al. Vitreous traction and epiretinal membranes in diabetic macular oedema using spectral-domain optical coherence tomography. Eye (London, England). 2010;24(10):1545-1553. https://doi.org/10.1038/eye.2010.80.
  28. Куликов А.Н., Сосновский С.В., Березин Р.Д., и др. Динамика патологии витреомакулярного интерфейса у больных с ДМО на фоне анти-VEGF-терапии / VII Всероссийский (с зарубежным участием) семинар-круглый стол «МАКУЛА-2016»; Ростов-на-Дону, 20–22 мая. – Ростов-на-Дону; 2016. [Kulikov AN, Sosnovskii SV, Berezin RD, et al. Dinamika patologii vitreomakulyarnogo interfeisa u bol’nykh s DMO na fone anti-VEGF-terapii. VII Vserossiiskii (s zarubezhnym uchastiem) seminar-kruglyi stol “MAKULA-2016”; dated 20-22 May. Rostov-na-Donu; 2016. (In Russ.)]
  29. Romano MR, Comune C, Ferrara M, et al. Retinal changes induced by epiretinal tangential forces. J Ophthalmol. 2015;2015:372564:372-564. https://doi.org/10.1155/2015/372564.
  30. Googe J, Brucker AJ, Bressler N, et al. Diabetic Retinopathy Clinical Research Network: randomized trial evaluating short-term effects of intravitreal ranibizumab or triamcinolone acetonide on macular edema after focal/grid laser for diabetic macular edema in eyes also receiving panretinal photocoagulation. Retina. 2011;31(6):1009-1027. https://doi.org/10.1097/IAE.0b013e318217d739.
  31. Ozsutcu M, Gulkilik G, Ayintap E, et al. Intravitreal bevacizumab may increase diabetic macular edema in eyes with attached posterior vitreous. Case Rep Ophthalmol. 2013;4(1):7-10. https://doi.org/10.1159/000342873.
  32. Panjaphongse R, Stewart JM. Vitreomacular traction after dexamethasone intravitreal implant (ozurdex) injection: the effect of anomalous posterior vitreous detachment. Retin Cases Brief Rep. 2016;10(1):55-57. https://doi.org/10.1097/ICB.0000000000000172.
  33. Wallraf SH, Markova K, Haritoglou C. [Vitreomacular traction following anti-VEGF therapy – two cases. (In German)]. Klin Monbl Augenheilkd. 2019;236(11):1339-1345. https://doi.org/10.1055/s-0043-121036.

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