About a new approach to surgical treatment of corneal endothelial dystrophy

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Abstract

Primary endothelial dystrophy of the cornea is a fairly common disease in people older than 50 years. Well-developed methods of conservative treatment, as a rule, do not lead to improvement or stabilization of the functional state of the cornea. The choice of tactics of surgical treatment from the existing variety of techniques is complicated. There are isolated reports of the restoration of corneal transparency after descemet membrane removal. The author's method of endothelial corneal dystrophy treatment addressed in this particular clinical case – a combination of isolated descemetorhexis and collagen cross-linking – resulted in impressive increase in visual acuity and significant improvement in objective criteria for the morpho-functional state of the cornea.

About the authors

Sergey Yu. Astakhov

Academician I.P. Pavlov First St. Petersburg State Medical University 

Author for correspondence.
Email: astakhov73@mail.ru

MD, PhD, DMedSc, professor, head of Ophthalmology Department

Russian Federation, Saint Petersburg

Inna A. Riks

Academician I.P. Pavlov First St. Petersburg State Medical University 

Email: riks0503@yandex.ru

MD, PhD, assistant, Ophthalmology Department

Russian Federation, Saint Petersburg

Sanasar S. Papanyan

Academician I.P. Pavlov First St. Petersburg State Medical University 

Email: dr.papanyan@yandex.ru

MD, aspirant, Ophthalmology Department

Russian Federation, Saint Petersburg

Sergey A. Novikov

Academician I.P. Pavlov First St. Petersburg State Medical University 

Email: serg2705@yandex.ru

MD, PhD, DMedSc, professor, Ophthalmology Department

Russian Federation, Saint Petersburg

Georgiy Z. Dzhaliashvili

Academician I.P. Pavlov First St. Petersburg State Medical University 

Email: zurabych@yandex.ru

Ophthalmologist

Russian Federation, Saint Petersburg

References

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Supplementary files

Supplementary Files
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1. JATS XML
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2. Fig. 1. Cornea of the right eye

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3. Fig. 2. Corneal topography and pachymetry

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4. Fig. 3. Cornea after descemetorhexis

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5. Fig. 4. Cornea 2 weeks after CXL

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6. Fig. 5. Cornea (arrows indicate the border of the descemetorhexis)

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7. Fig. 6. Anterior segment optical coherence tomography (arrows indicate the border of the descemetorhexis)

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8. Fig. 7. Cornea (arrows indicate the border of the descemetorhexis)

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9. Fig. 8. Confocal microscopy of endothelial cells (single endothelial cells are visible)

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10. Fig. 9. Confocal microscopy of endothelial cells 1546 cells/mm2 (а); morphological characteristics of endothelial cells by confocal microscopy (b)

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11. Fig. 10. Cornea of the right eye (arrows indicate the border of the descemetorhexis)

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12. Fig. 11. Corneal topography and pachymetry

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Copyright (c) 2018 Astakhov S.Y., Riks I.A., Papanyan S.S., Novikov S.A., Dzhaliashvili G.Z.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
 


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