About a new approach to surgical treatment of corneal endothelial dystrophy

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Primary endothelial dystrophy of the cornea is a fairly common disease in people older than 50 years. Well-developed methods of conservative treatment, as a rule, do not lead to improvement or stabilization of the functional state of the cornea. The choice of tactics of surgical treatment from the existing variety of techniques is complicated. There are isolated reports of the restoration of corneal transparency after descemet membrane removal. The author's method of endothelial corneal dystrophy treatment addressed in this particular clinical case – a combination of isolated descemetorhexis and collagen cross-linking – resulted in impressive increase in visual acuity and significant improvement in objective criteria for the morpho-functional state of the cornea.

作者简介

Sergey Astakhov

Academician I.P. Pavlov First St. Petersburg State Medical University 

编辑信件的主要联系方式.
Email: astakhov73@mail.ru

MD, PhD, DMedSc, professor, head of Ophthalmology Department

俄罗斯联邦, Saint Petersburg

Inna Riks

Academician I.P. Pavlov First St. Petersburg State Medical University 

Email: riks0503@yandex.ru

MD, PhD, assistant, Ophthalmology Department

俄罗斯联邦, Saint Petersburg

Sanasar Papanyan

Academician I.P. Pavlov First St. Petersburg State Medical University 

Email: dr.papanyan@yandex.ru

MD, aspirant, Ophthalmology Department

俄罗斯联邦, Saint Petersburg

Sergey Novikov

Academician I.P. Pavlov First St. Petersburg State Medical University 

Email: serg2705@yandex.ru

MD, PhD, DMedSc, professor, Ophthalmology Department

俄罗斯联邦, Saint Petersburg

Georgiy Dzhaliashvili

Academician I.P. Pavlov First St. Petersburg State Medical University 

Email: zurabych@yandex.ru

Ophthalmologist

俄罗斯联邦, Saint Petersburg

参考

  1. Антонова О.И. Современные аспекты диагностики и лечения первичной эндотелиальной дистрофии роговицы (Фукса): Дис. … канд. мед. наук. – М., 2016. [Antonova OI. Sovremennye aspekty diagnostiki i lecheniya pervichnoy endotelial'noy distrofii rogovitsy (Fuksa). [dissertation] Moscow; 2016. (In Russ.)]
  2. Рикс И.А., Папанян С.С., Астахов С.Ю., Новиков С.А. Новая клинико-морфологическая классификация эндотелиально-эпителиальной дистрофии роговицы // Офтальмологические ведомости. – 2017. – Т. 3. – № 3. – С. 46–52. [Riks IA, Papanyan SS, Astakhov SYu, Novikov SA. Novel clinico-morphological classification of the corneal endothelialepithelial dystrophy. Ophthalmology Journal. 2017;10(3):46-52. (In Russ.)]. doi: 10.17816/OV10346-52]
  3. Afshari NA, Pittard AB, Siddiqui BS, Klintworth GK. Clinical study of Fuchs corneal endothelial dystrophy leading to penetrating keratoplasty. A 30-year experience. Arch Ophthalmol. 2006;124(6):777-780. doi: 10.1001/archopht.124.6.777.
  4. Arbelaez JG, Price MO, Price FW. Long-term Follow-up and Complications of Stripping Descemet Membrane Without Placement of Graft in Eyes With Fuchs Endothelial Dystrophy. Cornea. 2014;33(12):1295-9. doi: 10.1097/ICO.0000000000000270.
  5. Balachandran C, Ham L, Verschoor CA, et al. Spontaneous corneal clearance despite graft detachment in descemet membrane endothelial keratoplasty. Am J Ophthalmol. 2009;148:227-234. doi: 10.1016/j.ajo.2009.02.033.
  6. Bleyen I, Saelens IA, van Dooren BT, et al. Spontaneous corneal clearing after Descemet’s stripping. Ophthalmology. 2013;120:215. doi: 10.1016/j.ophtha.2012.08.037.
  7. Borkar DS, Veldman P, Colby KA. Treatment of Fuchs endothelial dystrophy by descemet stripping without endothelial keratoplasty. Cornea. 2016;35:1267-1273. doi: 10.1097/ICO.0000000000000915.
  8. Braunstein RE, Airiani S, Chang MA, Odrich MG. Corneal edema resolution after “descemetorhexis.” Journal of Cataract and Refractive Surgery. 2003;29(7):1436-1439. doi: 10.1016/S0886-3350(02)01984-3.
  9. Choo SY, Zahidin AZM, Then KY. Spontaneous Corneal Clearance Despite Graft Detachment in Descemet Membrane Endothelial Keratoplasty. American Journal of Ophthalmology. 2010;149(3):531. doi: 10.1016/j.ajo.2009.11.010.
  10. Rao R, Borkar DS, Colby KA, Veldman PB. Descemet Membrane Endothelial Keratoplasty After Failed Descemet Stripping Without Endothelial Keratoplasty. Cornea. 2017;0(0):1-4. doi: 10.1097/ICO.0000000000001214.
  11. Dirisamer M, Ham L, Dapena I, et al. Descemet membrane endothelial transfer: “free-floating” donor Descemet implantation as a potential alternative to “keratoplasty”. Cornea. 2012;31(2):194-7. doi: 10.1097/ICO.0b013e31821c9afc.
  12. Galvis V, Tello A, Berrospi RD, et al. Descemetorhexis without endothelial graft in Fuchs dystrophy. Cornea. 2016;35:26-28. doi: 10.1097/ICO.0000000000000931.
  13. Ham L, Dapena I, Moutsouris K, et al. Persistent corneal edema after descemetorhexis without corneal graft implantation in a case of Fuchs endothelial dystrophy. Cornea. 2011;30:248-249. doi: 10.1097/ICO.0b013e3181eeb2c7.
  14. Iovieno A, Neri A, Am S, et al. Descemetorhexis Without Graft Placement for the Treatment of Fuchs Endothelial Dystrophy: Preliminary Results and Review of the Literature. Cornea. 2017;36(6):637-641. doi: 10.1097/ICO.0000000000001202.
  15. Koenig SB. Long-term Corneal Clarity After Spontaneous Repair of an Iatrogenic Descemetorhexis in a Patient With Fuchs Dystrophy. Cornea. 2013;32(6):886-8. doi: 10.1097/ICO.0b013e3182886aaa.
  16. Koenig SB. Planned Descemetorhexis Without Endothelial Keratoplasty in Eyes With Fuchs Corneal Endothelial Dystrophy. Cornea. 2015;34(9):1149-51. doi: 10.1097/ICO.0000000000000531.
  17. Krachmer JH, Purcell JJJr, Young CW, Bucher KD. Corneal endothelial dystrophy. A study of 64 families. Arch Ophthalmol. 1978;96:2036-9. doi: 10.1001/archopht.1978.03910060424004.
  18. Moloney G, Chan UT, Hamilton A, et al. Descemetorhexis for Fuchs’ dystrophy. Canadian Journal of Ophthalmology. 2015;50(1):68-72. doi: 10.1016/j.jcjo.2014.10.014.
  19. Moloney G, Petsoglou C, Ball M, et al. Descemetorhexis Without Grafting for Fuchs Endothelial Dystrophy-Supplementation With Topical Ripasudil. Cornea. 2017;36(6):642-648. doi: 10.1097/ICO.0000000000001209.
  20. Pan JCH, Eong KGA. Spontaneous resolution of corneal oedema after inadvertent “descemetorhexis” during cataract surgery. Clinical and Experimental Ophthalmology. 2006;34(9):896-897. doi: 10.1111/j.1442-9071.2006.01360.x.
  21. Patel DV, Phang KL, Grupcheva CN, et al. Surgical detachment of Descemet’s membrane and endothelium imaged over time by in vivo confocal microscopy. Clinical and Experimental Ophthalmology. 2004;32(5):539-42. doi: 10.1111/j.1442-9071.2004.00875.x.
  22. Shah RD, et al. Spontaneous corneal clearing after Descemet’s stripping without endothelial replacement. Ophthalmology. 2012;119(2):256-60. doi: 10.1016/j.ophtha.2011.07.032.
  23. Watson SL, Abiad G, Coroneo MT. Spontaneous resolution of corneal oedema following Descemet’s detachment. Clinical and Experimental Ophthalmology. 2006;34(8):797-799. doi: 10.1111/j.1442-9071.2006.01319.x.
  24. Zafirakis P, Kymionis GD, Grentzelos MA, Livir-Rallatos G. Corneal graft detachment without corneal edema after descemet stripping automated endothelial keratoplasty. Cornea. 2010;29(4):456-8. doi: 10.1097/ICO.0b013e3181b46bc2.
  25. Ziaei M, Barsam A, Mearza AA. Spontaneous corneal clearance despite graft removal in Descemet stripping endothelial keratoplasty in Fuchs endothelial dystrophy. Cornea. 2013;32(7):164-166. doi: 10.1097/ICO.0b013e31828b75a1.
  26. Zvi T, Nadav B, Itamar K, Tova L. Inadvertent descemetorhexis. Journal of Cataract and Refractive Surgery. 2005;31(1):234-235. doi: 10.1016/j.jcrs.2004.11.001.

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版权所有 © Astakhov S.Y., Riks I.A., Papanyan S.S., Novikov S.A., Dzhaliashvili G.Z., 2018

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此作品已接受知识共享署名 4.0国际许可协议的许可
 


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