The influence of pseudoexfoliative syndrome on corneal morphology based on in vivo confocal microscopy

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Abstract

Background: Confocal microscopy is a modern examination method that enables real-time, noninvasive in vivo imaging of the cornea, limb, and conjunctiva.

Aim: To evaluate the main morphological changes observed using confocal microscopy in patients with pseudoexfoliation (PEX) syndrome.

Methods: Overall, 21 patients were examined: 12 with PEX syndrome were enrolled in the examination group and nine patients without PEX in the control group.

Results: In patients with PEX, a decreased cell density in the epithelium and stroma of the cornea as well as a significant increase of hyper-reflective intercellular microdeposits and dendritic cells was observed (p < 0.05).

About the authors

Vitaly V. Potemkin

I.P. Pavlov First St Petersburg State Medical University

Author for correspondence.
Email: potem@inbox.ru

PhD, assistant professor. Department of Ophthalmology

Russian Federation, Saint Petersburg

Tatyana S. Varganova

Saint Petersburg State Hospital No 2

Email: varganova.ts@yandex.ru

Ophthalmologist

Russian Federation, Saint Petersburg

Evgeniy L. Akopov

I.P. Pavlov First St Petersburg State Medical University

Email: elacop@mail.ru

PhD, assistant professor. Department of Ophthalmology

Russian Federation, Saint Petersburg

Elena V. Ageeva

I.P. Pavlov First St Petersburg State Medical University

Email: ageeva_elena@inbox.ru

resident. Department of Ophthalmology

Russian Federation, Saint Petersburg

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Copyright (c) 2017 Potemkin V.V., Varganova T.S., Akopov E.L., Ageeva E.V.

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