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Post a Comment Comparison of results and quality of life in patients with thyroid eye disease after different methods of orbital decompression
- Authors: Zhu W.1, Katinas E.B.1,2, Solovyov M.M.1,2, Fedotova K.1, Yaremenko A.I.1, Chachanidze E.V.3, Potеmkin V.V.1,2
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Affiliations:
- Academican I.P. Pavlov First St. Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation
- City Multidisciplinary Hospital No. 2
- State Budgetary Educational Institution School No. 153 Frunzensky District
- Issue: Vol 13, No 3 (2020)
- Pages: 37-45
- Section: Interdisciplinary aspects
- URL: https://journals.rcsi.science/ov/article/view/50821
- DOI: https://doi.org/10.17816/OV50821
- ID: 50821
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Abstract
Purpose. To evaluate the changes in the quality of life of patients with thyroid eye disease after different methods of orbital decompression.
Materials and methods. The study included 24 patients (37 orbits) with thyroid eye disease, aged 41.6 ± 20.6 (from 20 to 79 years), 18 women and 6 men. The patients were divided into two groups. The first group included 12 patients (19 orbits) who underwent orbital fat decompression. The second group included 12 patients (18 orbits) who underwent endoscopic endonasal bony orbital decompression. The Graves’ ophthalmopathy quality of life questionnaire (GO-QOL) was completed before surgery, and 3 and 6 months after it. Outcome analysis included also the assessment of visual acuity, proptosis, eyelid retraction, and palpebral fissure height.
Results. The GO-QOL visual function scores in both groups did not change significantly in 3 and in 6 months after orbital decompression (p > 0.05): in the first group, before and after 6 months, scores were 69.27 ± 20.02 and 68.96 ± 18.44, in the second group – 53.13 ± 29.13 and 57.81 ± 23.56, respectively. An improvement in the GO-QOL visual function estimation was observed in those patients whose visual acuity improved after surgery. The GO-QOL facial appearance scores significantly improved 3 months after surgery, and continued to increase up to 6 months: in the first group, facial appearance scores improved from 23.96 ± 23.01 to 48.42 ± 25.56 (p = 0.004), in the second group — from 47.92 ± 21.04 to 66.15 ± 23.15 (p = 0.037).
Conclusions. Orbital decompression significantly improves the quality of life of patients with thyroid eye disease, this is primarily associated with an improvement in facial appearance.
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##article.viewOnOriginalSite##About the authors
Wen Zhu
Academican I.P. Pavlov First St. Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation
Author for correspondence.
Email: zhuwen@mail.ru
ORCID iD: 0000-0002-2070-0333
ResearcherId: AAO-4942-2020
MD, Oral and Maxillofacial Surgeon, Postgraduate Research Student of the Department of Dental and Maxillofacial surgery
Saint PetersburgElena B. Katinas
Academican I.P. Pavlov First St. Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation; City Multidisciplinary Hospital No. 2
Email: elena_katinas@mail.ru
ORCID iD: 0000-0002-7898-0219
MD, PhD, Assistant Professor of the Department of Otorhinolaryngology with Clinic; Otorhinolaryngologist
Russian Federation, Saint PetersburgMikhail M. Solovyov
Academican I.P. Pavlov First St. Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation; City Multidisciplinary Hospital No. 2
Email: mmsolovyov@gmail.com
ORCID iD: 0000-0003-2305-3466
MD, PhD, Assistant Professor of the Department of Dental and Maxillofacial surgery; Head of the Department of Maxillofacial Surgery
Russian Federation, Saint PetersburgKarolina Fedotova
Academican I.P. Pavlov First St. Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation
Email: karo-luna@mail.ru
ORCID iD: 0000-0002-8062-3827
SPIN-code: 6935-9837
ResearcherId: Y-8542-2018
MD, Ophthalmologist, Postgraduate Research Student of the Department of Ophthalmology with Clinic
Russian Federation, Saint PetersburgAndrey I. Yaremenko
Academican I.P. Pavlov First St. Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation
Email: ayaremenko@me.com
ORCID iD: 0000-0002-7700-7724
MD, PhD, DMedSc, Professor, Head of the Department of Dental and Maxillofacial surgery
Russian Federation, Saint PetersburgEkaterina V. Chachanidze
State Budgetary Educational Institution School No. 153 Frunzensky District
Email: evkozlova1@mail.ru
Teacher-Psychologist
Russian Federation, Saint PetersburgVitaly V. Potеmkin
Academican I.P. Pavlov First St. Petersburg State Medical University of the Ministry of Healthcare of the Russian Federation; City Multidisciplinary Hospital No. 2
Email: potem@inbox.ru
SPIN-code: 3132-9163
MD, PhD, Assistant Professor of the Department of Ophthalmology with Clinic; Ophthalmologist
Russian Federation, Saint PetersburgReferences
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