Choroid melanoma, developed from nevus

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Abstract

It is known that 25% of choroidal nevus are suspicious, and the risk of their malignanisation is 2-13% with a tendency to increase during follow-up me elongation. It is known that 5.8% undergoes malignancy within 5 years, and 13.9% of suspicious choroidal nevi undergoes malignancy within 10 years. In the article, a clinical case of choroidal melanoma development 5.5 years after the detection of suspicious nevus in a patient who refused to follow up is described. In the presented case, there was a combination of two risk factors of nevus malignisation, which significantly increases the likelihood of such an outcome. Long-term follow-up of patients is required from the first day of diagnosis “nevus of the choroid with signs of progression”.

About the authors

Alevtina S. Stoyukhina

Research Institute of Eye Diseases

Author for correspondence.
Email: a.stoyukhina@yandex.ru
ORCID iD: 0000-0002-4517-0324
SPIN-code: 6084-8052
Scopus Author ID: 56928348200
ResearcherId: AAG-7030-2019

PhD, Senior Research Associate of Department of Retina and Optical Nerve Pathology

Russian Federation, Moscow

Marina Yu. Lerner

S.P. Botkin City Clinical Hospital

Email: mlernerdoc@mail.ru

PhD, Head of ophthamooncology department

Russian Federation, Moscow

References

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Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 1. Fundus photo (а), early (b), middle (c) and late (d) stages of fluorescein angiography at the primary patient examination. Arrows indicate the nevus borders, – hyperfluorescent nevus center

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3. Fig. 2. Fundus photo after 5.5 years after first patient’s visit

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4. Fig. 3. OCT horizontal (a) and vertical (b) scans across the tumor: а – red arrows – slit-like pigment epithelium detachment, – hyperreflective content above the pigment epithelium detachment; b – blue arrows – single cavities under the Bruch’s membrane, – neuroepithelium detachment between the tumor apices

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5. Fig. 4. Fundus photo, 20 months after brachytherapy

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Copyright (c) 2020 Stoyukhina A.S., Lerner M.Y.

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This work is licensed under a Creative Commons Attribution 4.0 International License.
 


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