Modern opportunities for the prevention and treatment of inflammatory eye diseases of an infectious nature in children

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Abstract

The development of inflammatory diseases of the cornea and conjunctiva, as well as the occurrence of infectious complications of intraocular surgery, are largely associated with the presence of saprophytic and pathogenic microflora in the conjunctival cavity. This circumstance is more characteristic of children. At the same time, the possibilities of antibacterial therapy of inflammatory eye diseases of bacterial and chlamydial etiology, as well as perioperative prophylaxis of infectious complications of intraocular surgical procedures in children, have significantly expanded today. The widespread use of fluoroquinolones has significantly improved the treatment of children with acute and chronic bacterial conjunctivitis, keratitis, blepharitis, meibomyitis, chalazion, as well as those with chronic conjunctivitis of chlamydial etiology. At the same time, levofloxacin – fluoroquinolone of the 3rd generation, which is used in our country in the form of a 0.5% solution as eye drops Oftaquix® (Santen, Finland), has demonstrated high efficacy for this purpose. The widespread introduction of the original 0.5% levofloxacin (Oftaquix®), in the treatment regimen for children with inflammatory diseases of the cornea and conjunctiva, as well as for a perioperative prevention of infectious complications of surgical procedures involving them, is a promising way to solve the problem.

About the authors

Vladimir V. Brzheskiy

St. Petersburg State Pediatric Medical University, Ministry of Healthcare of Russia

Author for correspondence.
Email: vvbrzh@yandex.ru
ORCID iD: 0000-0001-7361-0270
Scopus Author ID: 56566741700
ResearcherId: B-6093-2017

PhD, Professor, Head of the Department of Ophthalmology

Russian Federation, Saint Petersburg

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