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Post a Comment Visual functions in patients with cytomegalovirus uveitis and HIV infection
- Authors: Sizova T.D.1,2, Khokkanen V.M.2, Zumbulidze N.G.2, Boiko E.V.2,3,4
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Affiliations:
- Saint Petersburg Center for Control of AIDS and Infectious Diseases
- North-Western State Medical University named after I.I. Mechnikov
- Kirov Military Medical Academy
- S.N. Fyodorov Eye Microsurgery Federal State Institution, the Saint Petersburg Branch
- Issue: Vol 15, No 3 (2022)
- Pages: 47-55
- Section: Original researches
- URL: https://journals.rcsi.science/ov/article/view/131576
- DOI: https://doi.org/10.17816/OV110957
- ID: 131576
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Abstract
BACKGROUND: Cytomegalovirus damage to the eye is the leading cause of loss of visual functions associated with HIV. Effective treatment of HIV-infected patients has changed the understanding of the clinical picture of cytomegalovirus uveitis (CMV-uveitis).
AIM: The aim of the work is to determine the prevalence, the structure of clinical forms and to evaluate visual functions in HIV-infected patients with CMV-uveitis.
MATERIALS AND METHODS: The study group consisted of 66 HIV-infected patients with CMV-uveitis (97 eyes), of which there were 27 men (40.9%), 39 women (59.1%). The average age was 39.6 ± 3.91 years. All patients had stage 4B of HIV infection according to V.V. Pokrovsky’s classification (2006). During the work, visometry, perimetry, biomicroscopy, ophthalmoscopy were used.
RESULTS: The main form of the disease is chorioretinitis, diffuse and generalized forms of the disease are diagnosed in 68.0% of cases. In predicting visual acuity, the leading regression criterion was the clinical form of the disease.
CONCLUSIONS: Diffuse and generalized forms of the disease prevailed in clinical practice. Localization of the chorioretinal process of a predominantly diffuse nature predetermined visual acuity, which in more than a third of cases met the criteria for blindness according to the WHO classification (1977).
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##article.viewOnOriginalSite##About the authors
Tatiana D. Sizova
Saint Petersburg Center for Control of AIDS and Infectious Diseases; North-Western State Medical University named after I.I. Mechnikov
Author for correspondence.
Email: tanja_sizova@list.ru
ORCID iD: 0000-0003-4089-1242
SPIN-code: 2939-5495
Ophthalmologist, PhD Student
Russian Federation, Saint Petersburg; Saint PetersburgValentina M. Khokkanen
North-Western State Medical University named after I.I. Mechnikov
Email: valentina.khokkanen@szgmu.ru
ORCID iD: 0000-0001-8096-5088
SPIN-code: 6536-4889
Dr. Sci. (Med.), Professor, Professor of the Ophthalmology Department
Russian Federation, Saint PetersburgNatalia G. Zumbulidze
North-Western State Medical University named after I.I. Mechnikov
Email: guramovna@gmail.com
ORCID iD: 0000-0002-7729-097X
SPIN-code: 4439-8855
Cand. Sci. (Med.), Associate Professor of Ophthalmology Department
Russian Federation, Saint PetersburgErnest V. Boiko
North-Western State Medical University named after I.I. Mechnikov; Kirov Military Medical Academy; S.N. Fyodorov Eye Microsurgery Federal State Institution, the Saint Petersburg Branch
Email: boiko111@list.ru
ORCID iD: 0000-0002-7413-7478
SPIN-code: 7589-2512
Dr. Sci. (Med.), Professor, Head of the Ophthalmology Department; Corresponding member of the Military Medical Academy; Director
Russian Federation, Saint Petersburg; Saint Petersburg; Saint PetersburgReferences
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