Analysis of retinal and optic nerve electrogenesis dynamics after vitrectomy for complicated catarct surgery

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Abstract

Background. The article presents impact results of vitrectomy for complicated cataract surgery on retinal and optic nerve electrogenesis.

Materials and methods. 30 patients (30 eyes) with history of dropped nucleus (1st group) or intraocular lens dislocated into the vitreous cavity after phacoemulsification (2nd group) underwent electrophysiological examination before vitrectomy, and on Day 1, Day 3, Day 7, Day 14, Day 30, Day 60, and Day 180 after surgery.

Results. In the 1st and 2nd groups, on the 1st day after vitrectomy, we observed a significant decrease in retinal and optic nerve electrogenesis in comparison to normal indices (p > 0.01); to Day 180, electrophysiologic indices returned to normal values. In the 1st group, baseline retinal and optic nerve electrogenesis was decreased in comparison to normal parameters. In the 1st and 2nd groups, the electrogenesis of photoreceptors recovered twice as rapidly, as that of bipolar cells; papillomacular bundle neurons were more resistant to vitrectomy.

Conclusion. Thus, the presence of lens nucleus fragments in the vitreous cavity results in a reliable inhibition of the retinal and optic nerve electrogenesis due to phacotoxic effect. Vitrectomy causes a short-term depression of the retinal and optic nerve electrogenesis, followed by normalization of indices to Day 180. Photoreceptors have greater rehabilitation activity than bipolar cells. The neurons of axial topographic orientation have the highest resistance to vitrectomy impact.

About the authors

Alexey N. Kulikov

Military Medical Academy of S.M. Kirov

Author for correspondence.
Email: alexey.kulikov@mail.ru
SPIN-code: 6440-7706

MD, PhD, DMedSc, Professor, Head of the Department. Ophthalmology Department

Russian Federation, St. Petersburg

Sergey V. Sosnovskii

Military Medical Academy of S.M. Kirov

Email: svsosnovsky@mail.ru
SPIN-code: 3058-7913

MD, Associate Professor of the Ophthalmology Department

Russian Federation, St. Petersburg

Evgeniya N. Nikolaenko

Military Medical Academy of S.M. Kirov

Email: e.n.nikolaenko@mail.ru
SPIN-code: 3517-0734

Ophthalmologist, Diagnostic Department

Russian Federation, St. Petersburg

References

  1. Бранчевский С.Л., Малюгин Б.Э. Распространённость нарушения зрения вследствие катаракты по данным исследования RAAB в Самаре // Офтальмохирургия. - 2013. - № 3. - C. 82-85. [Branchevsky SL, Malyugin BE. Incidence of visual impairment due to cataract according to the RAAB study in Samara. Ophthalmosurgery. 2013;(3):82-85. (In Russ.)]
  2. World Health Organization Study Group On. The prevention of blindness - report of a WHO Study Group. Technical report series. № 518. Geneva; 2012. W.H.O. - Режим доступа: www. whqlibdoc.who.int/trs/WHOTRS 518. pdf.
  3. Zhu M, Zhu J, Lu L, et al. Four-year analysis of cataract surgery rates in Shanghai, China: a retrospective cross-sectional study. BMC Ophthalmol. 2014;10(14):3-8. doi: 10.1186/1471-2415-14-3.
  4. Нероев В.В., Малюгин Б.Э., Трубилин В.Н., и др. Клинические и социальные аспекты лечения катаракты в России // Катарактальная и рефракционная хирургия. - 2016. - Т. 16. - № 1. - С. 4-14. [Neroev VV, Malyugin BE, Trubilin VN, et al. Clinical and social burden of cataract treatment in Russia. Cataractal and Refractive Surgery. 2016;16(1):4-14. (In Russ.)]
  5. Abulafia A, Rosen E, Assia EI, Kleinmann G. Establishment of a Registry to Monitor Trends in Cataract Surgical Procedures and Outcomes in Israel, 1990-2014. Isr Med Assoc J. 2015;17(12):755-759.
  6. Зуев А.В., Колесник А.И. Хирургическая тактика нетипичного течения факоэмульсификации катаракты. Ретроспективный анализ // Сборник материалов конференции «Современные технологии катарактальной и рефракционной хирургии - 2011». - M., 2011. - С. 87. [Zuev AV, Kolesnik AI. Khirurgicheskaya taktika netipichnogo techeniya fakoemul’sifikatsii katarakty. Retrospektivnyi analiz. In: Sbornik materialov konferentsii “Sovremennye tekhnologii kataraktal’noi i refraktsionnoi khirurgii - 2011”. (conference proceedings) Moscow; 2011. 87 p. (In Russ.)]
  7. Kолесников А.В. Мироненко Л.В., Свирина Т.А. Результаты субтотальной витрэктомии при дислокации интраокулярной линзы и фрагментов хрусталика в стекловидное тело // Сборник материалов конференции «Современные технологии лечения витреоретинальной патологии - 2012». - M., 2012. - С. 111. [Kolesnikov AV, Mironenko LV, Svirina TA. Rezul’taty subtotal’noi vitrektomii pri dislokatsii intraokulyarnoi linzy i fragmentov khrustalika v steklovidnoe telo. Sbornik materialov konferentsii “Sovremennye tekhnologii lecheniya vitreoretinal’noi patologii - 2012”. (conference proceedings) Moscow; 2012. 111 p. (In Russ.)]
  8. Кузнецова Н.А., Игумнова E.H., Титов А.В. Осложнения факоэмульсификации катаракты по материалам АО «АКОБ» за 2005-2012 гг. // Фёдоровские чтения - 2013: тезисы докладов научной конференции. - М., 2013. - С. 226. [Kuznetsova NA, Igumnova EH, Titov AV. Oslozhneniya fakoemul’sifikatsii katarakty po materialam AO “AKOB” za 2005-2012 gg. Moscow; 2013. 226 p. (In Russ.)]
  9. Ascaso FJ, Huerva V. Grzybowski A. Epidemiology, etiology, and prevention of late IOL-capsular bag complex dislocation: review of the literature. J Ophthalmol. 2015;2015:805-807. doi: 10.1155/2015/805706.
  10. Колесников А.В., Мироненко Л.В. Субтотальная витрэктомия при различной офтальмопатологии // Сборник материалов конференции «Восток - Запад - 2013». - Уфа, 2013. - С. 254. [Kolesnikov AV, Mironenko LV. Subtotal’naya vitrektomiya pri razlichnoi otftal’mopatologii. In: Sbornik materialov konferentsii “Vostok - Zapad - 2013”. (conference proceedings) Ufa; 2013. 254 p. (In Russ.)]
  11. Смирнов Е.В., Дружинин И.Б., Черных Д.В., и др. Витрэктомия с использованием эндоскопической техники при сочетанной патологии переднего и заднего отрезка глаза // Сборник материалов конференции «Современные технологии лечения витреоретинальной патологии - 2013». - M., 2013. - С. 170. [Smirnov EV, Druzhinin IB, Chernykh DV. et. al. Vitrektomiya s ispol’zovaniem endoskopicheskoi tekhniki pri sochetannoi patologii perednego i zadnego otrezka glaza. In: Sbornik materialov konferentsii “Sovremennye tekhnologii lecheniya vitreoretinal’noi patologii - 2013”. (conference proceedings) Moscow; 2013. 170 p. (In Russ.)]
  12. Худяков А.Ю., Васильев А.В. Результаты лечения дислокации фрагментов хрусталика в стекловидное тело при выполнении факоэмульсификации катаракты // Сборник материалов конференции «Современные технологии катарактальной и рефракционной хирургии. - 2008». - M., 2008. [Khudyakov AYu, Vasil’ev AV. Rezul’taty lecheniya dislokatsii fragmentov khrustalika v steklovidnoe telo pri vypolnenii fakoemul’sifikatsii katarakty. In: Sbornik materialov konferentsii “Sovremennye tekhnologii kataraktal’noi i refraktsionnoi khirurgii. - 2008”. (conference proceedings) Moscow; 2008. (In Russ.)]
  13. McCulloch DL, Marmor MF, Brigell MG, et al. ISCEV Standard for full-field clinical electroretinography (2015 update). Doc Ophthalmol. 2015;130(1):1-12. doi: 10.1007/s10633-014-9473-7.
  14. Odom JV, Bach M, Brigell M, et al. ISCEV Standard for clinical visual evoked potentials: (2016 update). Doc Ophthalmol. 2016;133(1):1-9. doi: 10.1007/s10633-016-9553-y.
  15. Шамшинова А.М. Электроретинография в офтальмологии. - M., 2009. [Shamshinova AM. Elektroretinografiya v oftal’mologii. Moscow; 2009. (In Russ.)]
  16. Гнездицкий В.В., Шамшинова А.М. Опыт применения вызванных потенциалов в клинической практике. - М., 2001. [Gnezditskii VV, Shamshinova AM. Opyt primeneniya vyzvannykh potentsialov v klinicheskoi praktike. Moscow; 2001. (In Russ.)]
  17. Millar ER, Steel DH. Small-gauge transconjunctival vitrectomy with phacoemulsification in the pupillary plane of dense retained lens matter on perfluorocarbon liquids after complicated cataract surgery. Graefes Arch Clin Exp Ophthalmol. 2013;251(7):1757-1762. doi: 10.1007/s00417-013-2293-8.
  18. Scupola A1, Abed E, Sammarco MG, et al. 25-Gauge pars plana vitrectomy for retained lens fragments in complicated cataract surgery. Ophthalmologica. 2015;234(2):101-108. doi: 10.1159/000434732.
  19. Rey A, Jürgens I, Dyrda A, et al. Surgical outcome of late in-the-bag intraocular lens dislocation treated with pars plana vitrectomy. Retina. 2016;36(3):576-581. doi: 10.1097/IAE.0000000000000738.

Supplementary files

Supplementary Files
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1. JATS XML
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2. Fig. 1. Dynamics of visual acuity

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3. Fig. 2. Dynamics of the A wave amplitude of the Full-field ERG, µV

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4. Fig. 3. Dynamics of the absolute inhibition of the A wave amplitude of the Full-field ERG, µV

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5. Fig. 4. Dynamics of the relative inhibition of the A wave amplitude of the Full-field ERG, %

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6. Fig. 5. Dynamics of the B wave amplitude of the Full-field ERG, µV

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7. Fig. 6. Dynamics of the absolute inhibition of the B wave amplitude of the Full-field ERG, µV

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8. Fig 7. Dynamics of the relative inhibition of the B wave amplitude of the Full-field ERG, %

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9. Fig. 8. Dynamics of the wave amplitude of the Flicker ERG, µV

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10. Fig. 9. Dynamics of the absolute inhibition of the amplitude of the Flicker ERG, µV

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11. Fig. 10. Dynamics of the relative inhibition of the amplitude of the Flicker ERG, %

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12. Fig. 11. Dynamics of the latency of the Р2 Flash VEP, мs

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13. Fig. 12. Dynamics of the absolute inhibition of the latency Р2 Flash VEP, ms

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14. Fig. 13. Dynamics of the relative inhibition of the latency Р2 Flash VEP, %

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15. Fig. 14. Dynamics of the latency N2 of the Flash VEP, ms

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16. Fig. 15. Dynamics of the absolute inhibition of the latency N2 of the Flash VEP, ms

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17. Fig. 16. Dynamics of the relative inhibition of the latency N2 Flash VEP, %

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18. Fig. 17. Dynamics of the electrical sensitivity, µA

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19. Fig. 18. Dynamics of the absolute inhibition of the electrical sensitivity, µA

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20. Fig. 19. Dynamics of the relative inhibition of the of the electrical sensitivity, %

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21. Fig. 20. Dynamics of the electrical lability, Hz

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22. Fig. 21. Dynamics of the absolute inhibition of the electrical lability, Hz

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23. Fig. 22. Dynamics of the relative inhibition of the electrical lability, %

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Copyright (c) 2018 Kulikov A.N., Sosnovskii S.V., Nikolaenko E.N.

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This work is licensed under a Creative Commons Attribution 4.0 International License.
 


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