Dydrogesterone (duphaston) and its 20-dihydro- metabolite as selective modulators of estrogenic enzymes in human breast cancer cells

封面


如何引用文章

全文:

详细

The presented data open up interesting prospects for studying the biological responses of progestogens in clinical trials in patients with breast cancer. Estradiol is one of the main factors that control the growth and development of breast cancer. Therefore, an important goal of research in recent years is to block the formation of estradiol inside cancer cells.

作者简介

Н. Thole

Solvay Pharmaceuticals GmbH

编辑信件的主要联系方式.
Email: info@eco-vector.com
德国, Hanover

G. Chetrite

Institut de Puericulture

Email: info@eco-vector.com

Hormones & Cancer Research Unit

法国, Париж

G. Philippe

Institut de Puericulture

Email: info@eco-vector.com

Hormones & Cancer Research Unit

法国, Париж

J. Pasqualini

Institut de Puericulture

Email: info@eco-vector.com

Hormones & Cancer Research Unit

法国, Париж

参考

补充文件

附件文件
动作
1. JATS XML
2. Fig. 1. The structure of progestogens: dydrogesterone and its metabolite 20-dihydro-dydrogesterone

下载 (10KB)
3. Fig. 3. The effect of dydrogesterone and its metabolite 20-dihydro-dydrogesterone on the conversion of estrone sulfate (E1S) to estradiol (E2) in hormone-dependent T-47D human breast cancer cell lines:

下载 (14KB)
4. Fig. 4. The effect of dydrogesterone and its metabolite 20-dihydro-dydrogesterone on the conversion of estrone (E1) to estradiol (E2) in hormone-dependent T-47D human breast cancer cell lines:

下载 (19KB)

版权所有 © Eсо-Vector, 2005



##common.cookie##