Email this article Dydrogesterone (duphaston) and its 20-dihydro- metabolite as selective modulators of estrogenic enzymes in human breast cancer cells
- Authors: Thole Н.Н.1, Chetrite G.S.2, Philippe G.S.2, Pasqualini J.R.2
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Affiliations:
- Solvay Pharmaceuticals GmbH
- Institut de Puericulture
- Issue: Vol 54, No 2 (2005)
- Pages: 67-72
- Section: Original Research
- URL: https://journals.rcsi.science/jowd/article/view/82486
- DOI: https://doi.org/10.17816/JOWD82486
- ID: 82486
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Abstract
The presented data open up interesting prospects for studying the biological responses of progestogens in clinical trials in patients with breast cancer. Estradiol is one of the main factors that control the growth and development of breast cancer. Therefore, an important goal of research in recent years is to block the formation of estradiol inside cancer cells.
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##article.viewOnOriginalSite##About the authors
Н. Н. Thole
Solvay Pharmaceuticals GmbH
Author for correspondence.
Email: info@eco-vector.com
Germany, Hanover
G. S. Chetrite
Institut de Puericulture
Email: info@eco-vector.com
Hormones & Cancer Research Unit
France, ПарижG. S. Philippe
Institut de Puericulture
Email: info@eco-vector.com
Hormones & Cancer Research Unit
France, ПарижJ. R. Pasqualini
Institut de Puericulture
Email: info@eco-vector.com
Hormones & Cancer Research Unit
France, ПарижReferences
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