Email this article Donors of nitric oxide in the treatment of preeclampsia: influence on the state of the endothelium and hemodynamics in the functional mother-placenta-fetus system
- Authors: Malakhovskaya E.A.1, Zainulina M.S.1
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Affiliations:
- State Medical University named after acad. I.P. Pavlova
- Issue: Vol 53, No 4 (2004)
- Pages: 42-45
- Section: Original Research
- URL: https://journals.rcsi.science/jowd/article/view/88641
- DOI: https://doi.org/10.17816/JOWD88641
- ID: 88641
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Abstract
We investigated influence of nitrovasodilators on functional status of endothelium in preeclampsia with measuring of thrombomodulin, sICAM-1 and sVCAM-1 plasma levels. Changes in feto-placental and uteroplacental hemodynamics were analysed after treatment with isosorbide mononitrate and isosorbide dinitrate. Our results showed efficacy of nitric oxide donors in complex therapy of preeclampsia.
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##article.viewOnOriginalSite##About the authors
Elena A. Malakhovskaya
State Medical University named after acad. I.P. Pavlova
Author for correspondence.
Email: info@eco-vector.com
candidate of medical sciences, obstetrician-gynecologist
Russian Federation, Saint-PetersburgMarina S. Zainulina
State Medical University named after acad. I.P. Pavlova
Email: info@eco-vector.com
Doctor of Medical Sciences, Professor, Doctor
Russian Federation, Saint-PetersburgReferences
