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Post a Comment Aspergillosis of the brain: diagnostic difficulties. Case report
- Authors: Verbakh T.E.1, Kicherova O.A.1, Reihert L.I.1, Ostapchuk E.S.1
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Affiliations:
- Tyumen State Medical University
- Issue: Vol 13, No 4 (2022)
- Pages: 88-92
- Section: Case reports
- URL: https://journals.rcsi.science/clinpractice/article/view/144173
- DOI: https://doi.org/10.17816/clinpract107997
- ID: 144173
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Abstract
Background: Neuroaspergillosis has nonspecific clinical manifestations and a severe course. Cases of central nervous system aspergillosis are becoming more frequent. Its lifetime diagnosis is very difficult. At the same time, a timely diagnosis makes it possible to conduct an adequate specific therapy and save the patient's life.
Clinical case description: We report a clinical case of a patient with a lethal damage to the brain by filamentous fungi, who did not have the risk factors described in the literature — human immunodeficiency virus (HIV), neutropenia, organ and tissue transplantation, long therapy with immunosuppressive drugs or corticosteroids.
Conclusion: One needs to consider a possibility of this pathology in patients even in the absence of a fever and immunodeficiency conditions. A specific study of biological fluids for the presence of the galactomannan antigen may allow one to establish a timely correct diagnosis and apply an adequate treatment.
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##article.viewOnOriginalSite##About the authors
Tatyana E. Verbakh
Tyumen State Medical University
Author for correspondence.
Email: shtork@yandex.ru
ORCID iD: 0000-0002-6294-1776
SPIN-code: 7776-4134
MD, PhD
Russian Federation, 1, Belyaev street, Tyumen, 625015Oksana A. Kicherova
Tyumen State Medical University
Email: pan1912@mail.ru
ORCID iD: 0000-0002-7598-7757
SPIN-code: 3162-0770
MD, PhD, Assistant Professor
Russian Federation, TyumenLyudmila I. Reihert
Tyumen State Medical University
Email: lir0806@gmail.com
ORCID iD: 0000-0003-4313-0836
SPIN-code: 1703-2302
MD, PhD, Professor
Russian Federation, TyumenEkaterina S. Ostapchuk
Tyumen State Medical University
Email: ostapchuk2008@mail.ru
ORCID iD: 0000-0003-1176-4113
SPIN-code: 6877-6140
Russian Federation, Tyumen
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