以心律和传导障碍为表现形式的糖尿病新面貌

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综述文章重点介绍了2型糖尿病背景下的心率变化,2型糖尿病是最常见的内分泌疾病之一。近年来,糖尿病与心律紊乱之间的关系日益密切。心动过速、心动过缓和心房颤动等心律失常在 2 型糖尿病患者中很常见,并可能对健康和生活质量产生严重影响。由于久坐不动的生活方式、超重、腹部肥胖以及饮食中含有过多脂肪和碳水化合物,2 型糖尿病在全球范围内越来越常见。胰岛素依赖型糖尿病是一种导致心脏自主神经病变的代谢性疾病,会影响交感和副交感神经纤维。这可以用血糖水平对心率变异性的不利影响来解释。尽管心血管反射测试被认为是评估心血管自主神经病变的金标准,但心脏功能最重要的指标之一是心率变异性的测量。这是两个连续收缩之间的变化:变化越大,副交感神经系统的活动越强。高心率变异性反映了一个人能够不断适应微环境的变化。因此,心率变异性低是心血管风险的标志。

作者简介

Mark S. Tyurypov

Military Medical Academy

编辑信件的主要联系方式.
Email: vmeda-nio@mail.ru
ORCID iD: 0000-0002-8366-0594
SPIN 代码: 2886-7181
俄罗斯联邦, Saint Petersburg

Polina O. Odnokol

Military Medical Academy

Email: vmeda-nio@mail.ru
ORCID iD: 0000-0003-2033-9610
SPIN 代码: 6660-7128
俄罗斯联邦, Saint Petersburg

Gennadiy G. Kutelev

Military Medical Academy

Email: vmeda-nio@mail.ru
ORCID iD: 0000-0002-6489-9938
SPIN 代码: 5139-8511
Scopus 作者 ID: 57226122182
Researcher ID: KGM-7824-2024

MD, Dr. Sci. (Medicine)

俄罗斯联邦, Saint Petersburg

Uliana A. Komarova

Military Medical Academy

Email: vmeda-nio@mail.ru
ORCID iD: 0009-0008-6729-2892
俄罗斯联邦, Saint Petersburg

参考

  1. Magliano DJ, Sacre JW, Harding JL, et al. Young-onset type 2 diabetes mellitus — implications for morbidity and mortality. Nat Rev Endocrinol. 2020;16(6):321–331. doi: 10.1038/s41574-020-0334-z
  2. Yun JS, Ko SH. Current trends in epidemiology of cardiovascular disease and cardiovascular risk management in type 2 diabetes. Metabolism. 2021;123:154838. doi: 10.1016/j.metabol.2021.154838
  3. Leopoulou M, Theofilis P, Kordalis A, et al. Diabetes mellitus and atrial fibrillation-from pathophysiology to treatment. World J Diabetes. 2023;14(5):512–527. doi: 10.4239/wjd.v14.i5.512
  4. Benichou T, Pereira B, Mermillod M, et al. Heart rate variability in type 2 diabetes mellitus: A systematic review and meta-analysis. PLoS One. 2018;13(4): e0195166. doi: 10.1371/journal.pone.0195166
  5. Joubert M, Manrique A, Cariou B, et al. Diabetes-related cardiomyopathy: The sweet story of glucose overload from epidemiology to cellular pathways. Diabetes Metab. 2019;45(3):238–247. doi: 10.1016/j.diabet.2018.07.003
  6. Shestakova M, Vikulova O, Zheleznyakova A, et al. Epidemiology of diabetes mellitus in the Russian Federation: what has changed over the past decade? Terapevticheskiy arkhiv. 2019;91(10):4–13. (In Russ.) EDN: BHBUBI doi: 10.26442/00403660.2019.10.000364
  7. Conning-Rowland M, Cubbon RM. Molecular mechanisms of diabetic heart disease: Insights from transcriptomic technologies. Diab Vasc Dis Res. 2023;20(6):14791641231205428. doi: 10.1177/14791641231205428
  8. Kanorsky SG, Kovalenko YuS. Features of development, the possibility of prevention and treatment of atrial fibrillation in patients with diabetes mellitus. South Russian Journal of Therapeutic Practice. 2023;4(1):19–27. EDN: BUTIJD doi: 10.21886/2712-8156-2023-4-1-19-27
  9. Demir K, Avci A, Kaya Z, et al. Assessment of atrial electromechanical delay and P-wave dispersion in patients with type 2 diabetes mellitus. J Cardiol. 2016;67(4):378–383. doi: 10.1016/j.jjcc.2015.06.003
  10. Katsiki N, Kotsa K, Stoian AP, et al. Hypoglycaemia and Cardiovascular Disease Risk in Patients with Diabetes. Curr Pharm Des. 2020;26(43):5637–5649. doi: 10.2174/1381612826666200909142658
  11. Subbotin AK, Tarlovskaya EI, Mazalova ME. Results of long-term ecg monitoring depending on the type of antihyperglycemic therapy in patients with type 2 diabetes. Neotlozhnaya kardiologiya i kardiovaskulyarnye riski. 2019; 3(1):526–531. (In Russ.) EDN: YKVMUS
  12. Motairek I, Al-Kindi S. Ameliorating Cardiovascular Risk in Patients with Type 2 Diabetes. Endocrinol Metab Clin North Am. 2023;52(1):135–147. doi: 10.1016/j.ecl.2022.07.002
  13. McRae M, Low Wang CC. Macrovascular Complications. Prim Care. 2022;49(2):255–273. doi: 10.1016/j.pop.2021.11.012
  14. Zabolotskikh IB, Bautin AE, Grigoriyev EV, et al. Perioperative management of patients with bradyarrhythmia. Anesteziologiya i reanimatologiya (Media Sfera). 2021;(6):6–24. (In Russ.) EDN: ZZHLLZ doi: 10.17116/anaesthesiology20210616
  15. Morgunov LYu. Diabetes mellitus and cardiac arrhythmia. Lechashchiy vrach. 2024;27(3):7–15. EDN: VBZOSU doi: 10.51793/OS.2024.27.3.001
  16. Lim LL, Chow E, Chan JN. Cardiorenal diseases in type 2 diabetes mellitus: clinical trials and real-world practice. Nat Rev Endocrinol. 2023;19(3):151–163. doi: 10.1038/s41574-022-00776-2
  17. Dillmann WH. Diabetic Cardiomyopathy. Circ Res. 2019;124(8):1160–1162. doi: 10.1161/CIRCRESAHA.118.314665
  18. Popov KA, Tokmakova AYu, Bondarenko IZ. Predictors and methods of diagnostics of myocardial autonomous innervation disorders in patients with type 1 and type 2 diabetes. Sakharnyi diabet. 2017;20(3):185–193. (In Russ.) EDN: ZCSJKF
  19. Krutikov ES, Tsvetkov VA, Chistyakova SI. Features of cardiac rhythm disturbances and assessment of their risk factors in patients with type 2 diabetes mellitus. Tavricheskiy Mediko-Biologicheskiy Vestnik. 2018;21(3):58–64. (In Russ.) EDN: YUKPED
  20. Shah A, Isath A, Aronow WS. Cardiovascular complications of diabetes. Expert Rev Endocrinol Metab. 2022;17(5):383–388. doi: 10.1080/17446651.2022.2099838
  21. O’Keefe JH, Nassif ME, Magwire ML, et al. The elephant in the room: Why cardiologists should stop ignoring type 2 diabetes. Prog Cardiovasc Dis. 2019;62(4):364–369. doi: 10.1016/j.pcad.2019.08.001
  22. Hoek AG, Dal Canto E, Wenker E, et al. Epidemiology of heart failure in diabetes: a disease in disguise. Diabetologia. 2024; 67(4):574–601. doi: 10.1007/s00125-023-06068-2
  23. Broni EK, Ndumele CE, Echouffo-Tcheugui JB, et al. The Diabetes-Cardiovascular Connection in Women: Understanding the Known Risks, Outcomes, and Implications for Care. Curr Diab Rep. 2022;22(1):11–25. doi: 10.1007/s11892-021-01444-x
  24. Coregliano-Ring L, Goia-Nishide K, Rangel ÉB. Hypokalemia in Diabetes Mellitus Setting. Medicina (Kaunas). 2022;58(3):431. doi: 10.3390/medicina58030431
  25. Prekina VI, Chernova IYu, Samolkina OG, et al. Heart rate variability in patients with diabetes mellitus and stroke. Russian Journal of Cardiology. 2022;27(S6):14. (In Russ.) EDN: JSPBUY
  26. Makarov LM, Komolyatova VN, Kupriyanova OO, et al. National Russian recommendations for the use of Holter monitoring techniques in clinical practice. Russian Journal of Cardiology. 2014;19(2):6–71. EDN: RXWMUZ
  27. Rydén L, Ferrannini G, Mellbin L. Risk factor reduction in type 2 diabetes demands a multifactorial approach. Eur J Prev Cardiol. 2019;26(2_suppl):81–91. doi: 10.1177/2047487319872015
  28. Zaveri MP, Perry JC, Schuetz TM, et al. Cancarevic I. Diabetic Cardiomyopathy as a Clinical Entity: Is It a Myth? Cureus. 2020;12(10): e11100. doi: 10.7759/cureus.11100
  29. Khodyrev GN, Khlybova SV, Tsirkin VI, et al. Methodological aspects of the analysis of temporal and spectral indicators of heart rate variability. Vyatka Medical Bulletin. 2011;(3–4):60–70. (In Russ.) EDN: TKOTLB

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2. Fig. 1. The main causes leading to cardiac arrhythmias and conduction disorders in patients with DM2

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