Features of the structure of cardiovascular diseases risk factors for complicated myocardial rupture myocardial infarction in young and middle-aged men

AIM: Myocardial rupture currently remains in most cases a fatal complication of myocardial infarction.

OBJECTIVE: To study the features of the structure of cardiovascular risk factors in men under 60 years old with complicated myocardial infarction to improve prevention.

MATERIALS AND METHODS: The study included men 19–60 years old with type I myocardial infarction. The patients were divided into two groups age-comparable: I – studied, with myocardial rupture – seven patients; II – control, without breaks – 558 patients. A comparative analysis of the frequency of observation of the main and additional factors of cardiovascular risk in the selected groups was performed.

RESULTS OF THE STUDY: In the patients of the study group, frequent (four or more times a year) colds were observed more often than in the control group (42.9 and 14.8%, respectively; p = 0.04), the internal organs foci of infections (85.7 and 40.3%; p = 0.049), bypass surgery (57.1 and 10.2%; p < 0.0001) and continuous cardiac pacing (28.6 and 0.5%; p < 0.0001) in medical history. The presence of arterial hypertension (28.5 and 67.6%; p = 0.03) and foci of oral cavity infections (0 and 20.3%; p = 0.049) reduced the risk of myocardial rupture. In the study group, the levels of total cholesterol (4.3 ± 0.3 and 5.8 ± 1.2 mmol/l); p = 0.02), low-density lipoproteins (2.7 ± 0.1 and 4.2 ± 1.2 mmol/l); p = 0.04) and triglycerides (0.7 ± 0.1 and 2.6 ± 1.8 mmol/l); p = 0.008) were lower than in the control.

CONCLUSION: Combinations of these cardiovascular risk factors indicate an increased risk of myocardial rupture. It is advisable to use them for predictive modeling of this event and the formation of risk groups for the purpose of timely prevention, (bibliography: 18 refs.).