PREOPERATIVE DIAGNOSIS OF COMPLICATIONS IN PATIENTS WHO HAVE UNDERGONE GASTROPANCREATODUODENAL RESECTION


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Abstract

The article presents a retrospective study of 64 patients with pancreatic pathology who underwent gastropancreatoduodenal resection. As a result of the study, it was noted that 33 patients developed postoperative complications, most of which were classified as grade III Clavien-Dindo. The analysis of the effectiveness of the new preoperative diagnostic score for pancreatic resections is performed. When calculating points on the PREPARE score, it was found that the expected (prognostic) low risk of developing postoperative complications corresponded to 48 patients, the intermediate - 10, and the high - 6. In fact, only 22 patients from the "low-risk" group had complications (6 - "mild" I-II degree in Cl.- D., 16- "heavy" III-V degree in Cl.- D.), 6 from the " intermediate " group (2 and 4, respectively) and 5 from the "high" group (all "heavy" III-V degree in Cl.- D.), which totaled 33 cases. Using ROC analysis, it was found that there were significant differences in PREPARE points (AUC=0.645, pAUC=0.047 [0.510-0.779]) and no differences in risk groups (AUC=0.601, pAUC=0.167 [0.461-0.740]). The results of the study indicate that the diagnostic score of preoperative diagnostics for pancreatic resections PREPARE may have a prognostic ability, when evaluated before surgery by points. Patients from the "high" risk prognostic group are of particular interest for the study. The use of the PREPARE score in patients who have undergone gastropancreatoduodenal resection can be an effective prognostic indicator of the development of postoperative complications, the need for and delay of the patient in the hospital, which will help reduce postoperative mortality. However, further research is needed on the predictive capabilities of the PREPARE score to include more patients.

About the authors

G. N Khrykov

Regional clinical oncology dispensary

St. Petersburg, Russia

V. S Dovganyuk

S.M. Kirov Military Medical Academy of the Ministry of Defense

St. Petersburg, Russia

N. N Burlov

S.M. Kirov Military Medical Academy of the Ministry of Defense

St. Petersburg, Russia

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