CHANGES IN HEART RATE VARIABILITY INDICATORS IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA SYNDROME

We studied heart rate variability in patients with obstructive sleep apnea in comparison with a group of healthy individuals without OSAS. The results obtained during the study showed that in patients with OSAS, there is a decrease in both temporal and spectral indicators of heart rate variability. We studied such indicators as the variational range of RR (VAR), the average value of all RR intervals, which gives an idea of the main level of functioning of the sinus node (avNN), the standard deviation of all NN intervals (SDNN), the number of consecutive pairs of RR intervals that differ more than 50 ms divided by the total number of all RR-intervals (pNN50), the standard deviation of the inter-interval differences, which estimates the high-frequency component of variability (rMSSD), the average of 5-minute standard deviations for the entire record (SDNNidx), standard e deviation of the values of the average NN intervals obtained for all 5-minute sections into which the registration period is divided (SDANN), the power of the very low-frequency domain (VLF), the power of the low-frequency domain of the HRV spectrum (LF), the power of the high-frequency domain of the HRV spectrum (HF), weighted average variation of the rhythmogram (SVR). Thus, it has been shown that in people with a syndrome of obstructive sleep apnea, a disturbance of the sympathoglobal balance occurs, which is a favorable factor for the occurrence of cardiovascular diseases and, in some cases, to lead to death. The obtained results emphasize the need for a more thorough examination of patients with OSAS for the presence of cardiovascular diseases and to relate these patients to the group of increased risk of their occurrence.

obstructive sleep apnea syndrome, heart rate variability, snoring, sympathetic-vagal balance, Holter ECG monitoring