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Post a Comment CHRONIC RENAL DISEASE PREDICTORS IN HYPERTENSIVE PATIENTS WITH ATRIAL FIBRILLATION
- Authors: Lebedeva Y.I1, Nekrutenko LN1, Tuev AV1
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Affiliations:
- Пермский государственный медицинский университет им. академика Е.А. Вагнера
- Issue: Vol 34, No 2 (2017)
- Pages: 45-50
- Section: Articles
- URL: https://journals.rcsi.science/PMJ/article/view/6786
- DOI: https://doi.org/10.17816/pmj34245-50
- ID: 6786
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Abstract
Aim. To determine the predictors of decreased glomerular filtration rate (GFR) in hypertensive patients with atrial fibrillation. Materials and methods. Thirty patients with II stage hypertensive disease (HD) associated with persisting form of atrial fibrillation were examined. The program of examination included blood serum biochemical analysis with creatinine determination, GFR calculation by CKD-EPI formula, echocardiography, hemostasis indices. The results were statistically processed using the program Statistica 10,0. Results. GFR level was decreased with patient’s aging ( R = -0,49, p = 0,0006), reduced cardiac ejection fraction ( R = 0,44, p = 0,0163), left atrium size enlargement ( R = -0,66, p = 0,0001), raised von Willebrand factor activity ( R = -0,40, p = 0,0286) and accelerated thrombin formation by the external path (prothrombin time) of blood coagulation ( R = 0,54, p = 0,0023). Conclusions. Willebrand factor activity, prothrombin time, cardiac ejection fraction, left atrium size and patient’s age are predictors of chronic renal disease formation in hypertensive patients with atrial fibrillation.
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##article.viewOnOriginalSite##About the authors
Yu I Lebedeva
Пермский государственный медицинский университет им. академика Е.А. Вагнера
Email: Julial.87@mail.ru
аспирант кафедры госпитальной терапии 614000, г. Пермь, ул. Петропавловская, д. 26
L N Nekrutenko
Пермский государственный медицинский университет им. академика Е.А. Вагнерадоктор медицинских наук, профессор кафедры госпитальной терапии 614000, г. Пермь, ул. Петропавловская, д. 26
A V Tuev
Пермский государственный медицинский университет им. академика Е.А. Вагнерадоктор медицинских наук, профессор, заведующий кафедрой госпитальной терапии 614000, г. Пермь, ул. Петропавловская, д. 26
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