Response of peripheral blood flow on apnea in young women with idiopathic arterial hypotension

Aim. To study the response of peripheral vessels hemodynamics to apnea in young women with idiopathic arterial hypotension.

Materials and methods. Comparative analysis of the results of ultrasonic scanning of peripheral arteries and veins using apnea test between 19 women with idiopathic arterial hypotension - SAP 98 (92-98) mm Hg and 11 women with normal arterial pressure - SAP 124 (121-126) mm Hg was carried out. Women’s age in both groups was 18-25 years. Arterial pressure and peripheral oxygen saturation were measured. Angioscanning in lying position and at rest as well as angioscanning prior to and 20 seconds after breath-holding was fulfilled. Diameter and blood velocity were estimated in the brachial, radial and posterior tibial arteries and veins.

Results. Apnea in young hypotensive women was found to induce increase in the diameter of a larger number of arteries than in the control group and fall in arterial blood velocity with the absence of venous blood velocity dynamics.

Conclusions. The abovementioned changes in the peripheral blood flow among women with hypotension are to be considered as manifestation of deadaptation, expressed by extreme endothelium-dependent dilatation of resistive vessels and inhibition of vasotonic response, probably, associated with excessive nitric oxide endothelial production.