EPIDEMIC PROCESS OF MEASLES INFECTION DURING ITS ELIMINATION PERIOD AND STRATEGIC DIRECTIONS OF CONTROL IN REAL TIME CONDITIONS

Aim. To determine the strategic directions for control of infection in the structure of supervision and control system in conditions of megapolis. In spite of significant success in fight against measles, this infection still remains dangerous for the population. Materials and methods. The data of official registration of measles sickness rate among Ekaterinburg population for 1988-2016 and the results of serological investigation of different groups of the population for anti-measles IgG were used as study materials. The population engaged into the study: industrial workers (118), medical staff (369), staff and students of medical higher school (258). Epidemiological, serological and statistical methods of study were used. Results. For the studied period, epidemic process of measles infection on the territory of Ekaterinburg was intermittent. Against the background of sickness rate fall there were registered local ictuses. A share of persons with seroprotection in different age and professional groups was established to be from 63% to 83%; the greatest part of persons with protective level was observed at the age over fifty. It was detected that 10 and more years after the last vaccination, 30-40% of the examined patients are deprived of protective level of antibodies. Conclusions. To control the epidemic situation for measles, it is necessary to cover with measles immunization not less than 95-98 % of children in indicator groups and not less than 85 % of all the population; the age for measles immunization should be prolonged among adults to 55 years (among all groups of the population) with revaccination every 10 years.

Measles, epidemic process, serological study, vaccinal prevention