Frequency of endemic goiter and indicators of pituitary-thyroid profile in Arctic children

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Abstract

Objective. Analysis of the frequency of endemic goiter and indicators of the pituitary-thyroid profile in children aged 10-18 years living in the Arctic regions of Yakutia.

Materials and methods. The study was conducted among children and adolescents of the Arctic regions of Yakutia (Bulunsky, Anabarsky, Allaikhovsky, Nizhnekolymsky, Verkhnekolymsky district) during field medical expeditions in 2018–2020. A total of 392 children aged 10–18 years were examined.

Results. In 30 % of the examined children, an increase in the thyroid gland was observed, which was accompanied by elevated levels of free thyroxine. In 3 % of children, an increase in the level of thyroid-stimulating hormone was detected against the background of reduced or normal levels of free thyroxine.

Conclusions. As for the prevalence of cases of endemic goiter, the Arctic regions of Yakutia are the areas of severe goiter endemia. The results obtained justify the need for additional scientific studies to assess the degree of iodine availability (by the concentration of iodine in the urine) in different population groups and real implementation of the strategy of mass preventive measures.

About the authors

S. A. Evseeva

Yakut Scientific Center for Complex Medical Problems

Email: bourtsevat@yandex.ru

Candidate of Medical Sciences, senior researcher

Russian Federation, Yakutsk

T. E. Burtseva

Yakut Scientific Center for Complex Medical Problems; North-Eastern Federal University named after M. K. Ammosov

Author for correspondence.
Email: bourtsevat@yandex.ru
ORCID iD: 0000-0002-5490-2072

MD, PhD, Professor, Department of Pediatrics and Pediatric Surgery

Russian Federation, Yakutsk

T. M. Klimova

Yakut Scientific Center for Complex Medical Problems; North-Eastern Federal University named after M. K. Ammosov

Email: bourtsevat@yandex.ru

Candidate of Medical Sciences, Associate Professor, Department of Pharmacology

Russian Federation, Yakutsk

N. A. Danilov

North-Eastern Federal University named after M. K. Ammosov

Email: bourtsevat@yandex.ru

postgraduate student

Russian Federation, Yakutsk

V. G. Chasnyk

Saint Petersburg State Pediatric Medical University

Email: bourtsevat@yandex.ru

MD, PhD, Head of Department of Hospital Pediatrics

Russian Federation, St. Petersburg

N. I. Douglas

North-Eastern Federal University named after M. K. Ammosov

Email: bourtsevat@yandex.ru

MD, PhD, Head of Department of Obstetrics and Gynecology

Russian Federation, Yakutsk

References

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Copyright (c) 2021 Evseeva S.A., Burtseva T.E., Klimova T.M., Danilov N.A., Chasnyk V.G., Douglas N.I.

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