CHANGES IN BLOOD FREE FATTY ACID CONTENT AMONG CHILDREN WITH LATENT FORM OF CHRONIC RENAL FAILURE

Aim. To assess the status of blood free fatty acid balance in children with megaureter diagnosed latent form of chronic renal failure. Materials and methods. The study design: prospective, controlled, nonrandomized, one-centered. The study included 40 children, divided into 2 groups. The main group ( n = 22) - patients after surgical intervention for megaureter with developing renal dysfunction. The comparison group - 18 relatively healthy children with a mean age of 6,1 ± 1,3 years. Results. It was revealed by the authors that in patients of the main group statistically significantly raised the content of a number of fatty acids. When conducting correlation analysis between the levels of blood total protein, erythrocytes and leukocytes with free fatty acid pool, it was detected that there are reliable, differently directed strong correlations between some of them. Conclusions. Children, who underwent surgical intervention for megaureter followed by development of latent chronic renal failure, differ from healthy children by both total protein content and qualitative composition of blood free fatty acids.

Chronic renal disease, children, fatty acids