CLINICOFUNCTIONAL CHARACTERISTIC OF PATIENTS WITH ACUTE CORONARY SYNDROME WITHOUT ST SEGMENT ELEVATION AGAINST THE BACKGROUND OF ACUTE ATRIAL FIBRILLATION

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Abstract

Aim. To study the clinicofunctional peculiarities of patients with acute coronary syndrome without ST segment elevation (ACSwSTE) against the background of acute atrial fibrillation (AF); to estimate the effect of AF on short-term prognosis in this group of patients. Materials and methods. Seventy one patients aged 62, [57; 70] including 38 women and 33 men, who were admitted to intensive cardiology unit with diagnosis of ACSwSTE, were examined. These patients were divided into 2 groups: group1 - ACSwSTE with acute AF, group 2 - ACSwSTE without AF. Patients’ examination, besides general clinical study, included echocardiography. Hospital lethality for the period of observation was analyzed. Results. In the group of patients suffering from ACSwSTE with AF there prevailed men. The course of ACSwSTE against the background of AF was accompanied by moderate decrease in glomerular filtration rate. According to ECG data, AF patients more often had the left ventricular myocardial hypertrophy and left atrium dilatation. Over the observation period no lethal outcomes were registered. Conclusions. Among patients with AF and ACSwSTE, enlargement of the left atrium, left atrial volume and left ventricular myocardium mass index was detected. Regardless of the common opinion, AF does not cause growth of hospital lethality in patients with ACSwSTE.

About the authors

I S Metelev

Кировская государственная медицинская академия

Email: rybanalim@rambler.ru
аспирант кафедры факультетской терапии

O V Soloviev

Кировская государственная медицинская академия

доктор медицинских наук, профессор, заведующий кафедрой факультетской терапии

E L Onuchina

Кировская государственная медицинская академия

кандидат медицинских наук, доцент кафедры факультетской терапии

S K Kononov

Кировская государственная медицинская академия

кандидат медицинских наук, ассистент кафедры факультетской терапии

References

  1. Болезни сердца по Браунвальду: руководство по сердечно-сосудистой медицине. Под ред. П. Либби; пер. с англ. под общ. ред. Р.Г. Оганова: в 4 т. Т. 1. Главы 1-20. М.: Рид Элсивер 2010; 101-120.
  2. Онучина Е.Л., Соловьев О.В., Мочалова О.В. Пациент с метаболическим синдромом: факторы риска развития фибрилляции предсердий. Практическая медицина 2010; 4 (43): 139-142.
  3. Рекомендации по количественной оценке структуры и функции камер сердца. Российский кардиологический журнал 2012; 3 (95): 3-28.
  4. Эрлих Д.А. Острый коронарный синдром и сопутствующая патология: характеристики пациентов, особенности лечения и исходы за время госпитализации. Ишемическая болезнь сердца 2014; Consilium medicum 2014; 16 (5): 33-37.
  5. Abed H.S., Wittert G.A., Leong D.P. Effect of weight reduction and cardiometabolic risk factor management on symptom burden and severity in patients with atrial fibrillation: a randomized clinical trial. JAMA 2013; 310 (19): 2050-2060.
  6. Alonso A., Lopez F.L., Matsushita K. Chronic kidney disease is associated with the incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study. Circulation 2011; 123 (25): 2946-2953.
  7. Anter E., Jessup M., Callans D.J. Atrial fibrillation and heart failure: treatment considerations for a dual epidemic. Circulation 2009; 119: 2516-2525.
  8. Bansal N. Intersection of cardiovascular disease and kidney disease: atrial fibrillation. Curr Opin Nephrol Hypertens 2014; 23 (3): 275-282.
  9. Devereux R.B., Alomso D.R., Lutas E.M. Echocardiographic assessment of left ventricular hypertrophy comparison to necropsy findings. Am J Cardiol 1986; 57: 450-458.
  10. Go A.S., Hylek E.M., Phillips K.A. Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the anticoagulation and risk factors in atrial fibrillation (ATRIA) study. J Amer Med Assoc 2001; 285: 2370-2375.
  11. Jabre P., Roger V.L., Murad M.H. Mortality associated with atrial fibrillation in patients with myocardial infarction: a systematic review and meta-analysis. Circulation 2011; 123 (15): 1587-1593.
  12. Kinjo K. Prognostic significance of atrial fibrillation. Am J Cardiol 2003; 92: 1150-1154.
  13. Lehto M. Prognostic risk of atrial fibrillation in acute myocardial infarction complicated by left ventricular dysfunction: the OPTIMAAL experience. Eur Heart J 2005; 26: 350-356.
  14. Roberts P.R. Arrhythmias in chronic kidney disease. Heart 2011; 97 (9): 766-773.
  15. Roy D., Talajic M., Thibault B. Pilot study and protocol of the Canadian Trial of Atrial Fibrillation (CTAF). Am J Cardiol 1997; 80 (4): 464-468.
  16. Saczynski J.S., McManus D., Zhou Z. Trends in atrial fibrillation complicating acute myocardial infarction. Am J Cardiol 2009; 104 (2): 169-174.
  17. Schmitt J., Duray G., Gersh B.J. Atrial fibrillation in acute myocardial infarction: a systematic review of the incidence, clinical features and prognostic implications. European Heart Journal 2009; 30 (9): 1038-1045.
  18. Torres M., Rocha S., Marques J. Impact of atrial fibrillation in acute coronary syndromes. Rev Port Cardiol 2008; 27 (11): 1407-1418.
  19. Whitlock G. Body-mass index and cause-specific mortality in 900,000 adults: collaborative analyses of 57 prospective studies. Lancet 2009; 373: 1083-1096.
  20. Zimmerman D., Sood M.M., Rigatto C. Systematic review and meta-analysis of incidence, prevalence and outcomes of atrial fibrillation in patients on dialysis. Nephrol Dial Transplant 2012; 27: 3816-3822.

Copyright (c) 2016 Metelev I.S., Soloviev O.V., Onuchina E.L., Kononov S.K.

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