MODERN PECULIARITIES OF PEDIATRIC BILIARY DYSFUNCTION COURSE

Aim. The aim was to study the modern clinicolaboratory peculiarities of biliary dysfunction course in children. Materials and methods. Fifty children (aged 7-14 years) with biliary dysfunction were under observation. Complex examination with studying of biochemical and functional indices (ultrasound investigation of abdominal cavity, duodenal intubation) was carried out. Results. Biliary dysfunction in the observed children often was combined with gastritis (94,0 %), duodenitis (84,0 %), pancreatic reactive changes (74,0 %). Clinical picture of this functional disorder was characterized by prevailing abdominalgia (96,0 %), dyspeptic syndrome in the form of eructation (74,0 %), nausea (70,0 %), absence of appetite (70,0 %). More often, gall bladder hypokinesia (54,0 %) and Oddi’s sphincter hypertonus (52,0 %) were diagnosed. Billiary dysfunction was accompanied by gall bladder wall thickening (76,0 %) and increased hepatic bile flow rate (3,0 ± 0,4). Conclusions. Pediatric biliary dysfunction is often one of the components of esophageal comorbid status causing occurrence of organic gastrointestinal lesions. Early diagnosis of this functional disorder followed by prophylactic measures for prevention of the development of gastrointestinal pathology is required.

Biliary dysfunction, gall bladder, Oddi’s sphincter