Disturbances of carbohydrate metabolism and postoperative complications after distal pancreatic resection

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Abstract

Objective. To study the state of carbohydrate metabolism in patients after distal pancreatic resection and its effect on the development of postoperative complications.

Materials and methods. Over 10 years, 47 patients have been operated on with various tumors of the body/tail of the pancreas and complications of chronic pancreatitis. In 16 of them, concomitant diabetes mellitus was diagnosed before surgery, and in 31 patients, carbohydrate metabolism was normal.

Results. After surgery, from a group of patients with unchanged carbohydrate metabolism, 8 (25.8 %) developed diabetes mellitus. The following postoperative complications – pancreatic fistula, inflammatory infiltrates and "fluid leakages” in the abdominal cavity – occurred in 68 % of cases. Out of 24 patients with diabetes mellitus, complications were registered in 21 (87.5 %) and of 23 diabetes-free patients – in 11 (47.8 %).

Conclusions. The total risk for the development of the postoperative abdominal complications after the distal resection in patients with diabetes mellitus, diagnosed before and after the intervention, is 7.6 times higher than in patients without diabetes.

About the authors

V. N. Barykov

South-Ural State Medical University

Author for correspondence.
Email: barykov50@mail.ru

MD, PhD, Professor, Head of Department of Hospital Surgery

Russian Federation, Chelyabinsk

A. G. Istomin

Chelyabinsk Regional Clinical Hospital

Email: barykov50@mail.ru

surgeon, First Surgical Unit

Russian Federation, Chelyabinsk

N. V. Markina

South-Ural State Medical University

Email: barykov50@mail.ru

Candidate of Technical Sciences, Associate Professor, Head of Department of Mathematics, Medical Informatics and Statistics, Physics

Russian Federation, Chelyabinsk

V. L. Tyulganova

Chelyabinsk Regional Clinical Hospital

Email: barykov50@mail.ru

Candidate of Medical Sciences, Head of Endocrinological Unit

Russian Federation, Chelyabinsk

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Copyright (c) 2020 Barykov V.N., Istomin A.G., Markina N.V., Tyulganova V.L.

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