CLINICOLABORATORY PARALLELS BETWEEN SPECIES COMPOSITION OF ORAL MICROBIOTA AND GENERAL SOMATIC PATHOLOGY IN PATIENTS WITH PERIODONTITIS

Aim. To establish the presence and character of relationship between species composition of microorganisms associated with periodontitis and concomitant somatic pathology. Materials and methods. 106 patients with periodontitis (observation group) and 66 patients without parodentium pathology were examined after oral cavity sanation (comparison group). Test-systems developed by us were used to study with PCR method the occurrence rate of P. gingivalis, T. denticola, S.oralis, S. sanguis, S. mutans, S. salivarius, S. sobrinus, S. macacae in the dental parodontal pocket and saliva content . Results. General somatic pathology among periodontitis patients was registered more often (by 33,2 %) than in comparison group ( p =0,0001). At the same time, in the group of observation, patients with periodentitis and general somatic pathology had parodontal pocket S. mutans, S. oralis, S. sobrinusus reliably more often (by 45 %, 43,2 % and 33,8 %, respectively, p <0,01) than patients of the same group without concomitant somatic pathology. Conclusions. Among patients with chronic periodontitis, qualitative changes in oral microbiocenosis are associated with functional status of different organs and systems of macroorganism.

Periodontitis, general somatic pathology, parodontopathogenic microflora, polymerase chain reaction