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Post a Comment COMPARATIVE CLINICONEUROPSYCHOLOGICAL ASSESSMENT OF COGNITIVE DISORDERS IN PATIENTS WITH ALZHEIMER’S DISEASE, VASCULAR AND MIXED COGNITIVE DISTURBANCES AT DIFFERENT STAGES OF COGNITIVE DEFICIENCY
- Authors: Mantashova AM1
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Affiliations:
- Пермская государственная медицинская академия им. ак. Е. А. Вагнера, Центр когнитивных нарушений, г. Пермь, Россия
- Issue: Vol 30, No 3 (2013)
- Pages: 30-36
- Section: Articles
- URL: https://journals.rcsi.science/PMJ/article/view/3418
- DOI: https://doi.org/10.17816/pmj30330-36
- ID: 3418
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Abstract
Aim. To compare clinical manifestations and neuropsychological profile of cognitive disorders in patients with Alzheimer’s disease, vascular and mixed vasculodegenerative cognitive disorders at different stages of cognitive deficiency. Materials and methods. In 106 patients of The Center of Cognitive Disorders the status of four cognitive domains including memory, speech, visual-spatial and regulatory-dynamic functions was estimated during complex neuropsychological examination. Results. The applied method of comparing of neuropsychological parameters of patients at the identical stage of cognitive deficiency showed that differences in cognitive profiles between the indicated groups depend on the stage of the process. Conclusion. Differential diagnosis of three considered in the paper cognitive disorders types can be completely performed only at the stage of moderate dementia with evaluation of episodic, semantic memory and visual-spatial functions.
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##article.viewOnOriginalSite##About the authors
A M Mantashova
Пермская государственная медицинская академия им. ак. Е. А. Вагнера, Центр когнитивных нарушений, г. Пермь, Россия
Email: mantashova_anna@mail.ru
аспирант кафедры спортивной медицины и реабилитологии с курсом геронтологии
References
- Левин О. С. Диагностика и лечение деменции в клинической практике. М.: МЕДпресс-информ 2010; 256.
- Черкасова В. Г. Вторичные церебральные атрофии: клиническая характеристика, диагностика и возможности терапии: автореф. дис. … д-ра мед. наук. Пермь 2005; 33.
- Шестаков В. В., Кулеш А. А. Нейропсихологический профиль когнитивных нарушений в остром периоде ишемического инсульта. Пермский медицинский журнал 2011; 28: 17–21.
- Graham N. L., Emery T., Hodges J. R. Distinctive cognitive profiles in Alzheimer’s disease and subcortical vascular dementia. J. Neurol. Neurosurg. Psychiatry 2004; 75: 61–71.
- Hort J., O’Brien J. T., Gainotti G. et al. EFNS guidelines for the diagnosis and management of Alzheimer’s disease. European Journal of Neurology 2010; 17: 1236–1248.
- Reed B. R., Mungas D. M., Kramer J. H. et al. Profiles of neuropsychological impairment in autopsy-defined Alzheimer’s disease and cerebrovascular disease. J. Brain 2007; 130: 731–739.
- Willem J. R. Bossers, Lucas H. V. Van der Woude, Froukje Boersma et al. Recommended mesures for the assesment of cognitive and physical performance in older patients with dementia: a systematic review. J. Dement. Geriatr. Cogn. Disord. Extra 2012; 2: 589–609.
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