HEREDITARY ANGIONEUROTIC EDEMA IN 18 YEAR-OLD PATIENT

The problem of isolated angioedemas is a difficult problem of clinical allergology, their prevalence needs further studies. Hereditary angioedema occurs rarely and makes not more than 2% of all angioedema cases, in the total population hereditaty angioedema is detected with the rate of 1:10000-1:1500000 persons. There are three forms of this disease: type I hereditary angioedema, type II hereditary angioedema and estrogen-dependent edemas (type III). The first two forms are conditioned by genetically deterministic absolute or relative deficit of C1-inhibitor, in the third form its concentration and function are not changed. Hereditary angioedemas, unfortunately, are incurable for today in spite of achievements of current medicine. However, in case of full anamnesis available, target diagnosis and timely onset of treatment it is possible to have a significant positive dynamics in the course of disease. In medical science there is a poor experience regarding this nosology that motivated us to publish a report on such a rare clinical case.

Angioedema, complement, C1-exterase inhibitor