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Post a Comment CORRELATION BETWEEN MICRO- AND MACRO-STRUCTURAL CEREBRAL MAGNETORESONANCE INDICES AND CLINICAL-FUNCTIONAL STATUS OF PATIENTS WITH ACUTE ISCHEMIC STROKE
- Authors: Kulesh AA1, Drobakha VE2, Shestakov VV1
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Affiliations:
- Пермский государственный медицинский университет им. академика Е. А. Вагнера
- Городская детская клиническая больница № 15
- Issue: Vol 32, No 5 (2015)
- Pages: 44-51
- Section: Articles
- URL: https://journals.rcsi.science/PMJ/article/view/3160
- DOI: https://doi.org/10.17816/pmj32544-51
- ID: 3160
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Abstract
Aim. To assess the correlation between micro and macrostructural cerebral magnetoresonance indices and clinical-functional status of patients with ischemic stroke in its acute period. Materials and methods. One hundred and three patients in the acute period of ischemic stroke underwent complex MRT study of the brain with assessment of morphometric indices and fractional anisotropy (FA) of 10 zones including 5 tracts of white substance. The obtained data were analyzed in context of correlation with neurological, cognitive and functional status of patients. Results. Differences in fractional anisotropy on the side of acute ischemic stroke and in the opposite hemisphere were revealed. The focus size is connected with the severity of neurological deficit, cognitive and functional status, but not with the status of tracts. Leucoareosis area and ventricular system volume are associated with neurological, cognitive and functional status as well as with the microstructure of thalamus, hippocampus, anterior limb of internal capsule, cingulate fascicle, frontooccipital fascicle and corpus callosum. The volume of hippocampus is associated only with FA of cingulate fascicle, but not with clinical data. Conclusions. The obtained data can testify adaptive mechanisms, which can start realizing at the microstructural level already in the acute period of ischemic stroke. Chronic vascular cerebral injury is the most significant factor influencing microstructure of gray and white substance of the brain along with the focal size determining neurological, cognitive and functional status in acute stroke patients.
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##article.viewOnOriginalSite##About the authors
A A Kulesh
Пермский государственный медицинский университет им. академика Е. А. Вагнера
Email: aleksey.kulesh@gmail.com
кандидат медицинских наук, доцент кафедры неврологии с курсом нейрореабилитологии ДПО
V E Drobakha
Городская детская клиническая больница № 15врач-рентгенолог
V V Shestakov
Пермский государственный медицинский университет им. академика Е. А. Вагнерадоктор медицинских наук, профессор, заведующий кафедрой неврологии с курсом нейрореабилитологии ДПО
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