ENTERAL INSUFFICIENCY SYNDROME AND ITS MANIFESTATIONS IN ACUTE PANCREATITIS PATIENTS

Aim. To estimate the peculiarities of enteral insufficiency syndrome course in patients with acute pancreatitis. Materials and methods. Examination was performed in 949 patients with acute pancreatitis. Enteral insufficiency syndrome (EIS) severity was assessed taking into account the degree of severity of acute pancreatitis as well as the level of endogenous intoxication in this category of patients. Results. Among patients with mild degree of acute pancreatitis, enteral insufficiency syndrome was absent in 50,1 % (289 persons) of patients. Patients with moderate acute pancreatitis in 51,4 % (129 persons) had degree I EIS, in 24,3 % (61 persons) - degree II and in 9,2 % (23 persons) - degree III. No EIS was detected in 15,1 % (38 persons) of patients. Among patients with severe pancreatitis, II and III degrees of EIS were revealed in all the cases - 71,9 % (87 persons) and 28,1 % (34 persons), respectively. Patients with acute pancreatitis were proved to have correlation effect of enteral insufficiency syndrome on progression of endogenous intoxication ( r = 1,218; р < 0,05). Conclusions. There is direct correlation between the enteral insufficiency syndrome and the acute pancreatitis severity. Besides, there was noted direct correlation dependence between the degree of manifestation of enteral insufficiency syndrome and the endogenous intoxication, developing against the background of the basic disease.

Pancreatitis, enteral insufficiency syndrome, endogenous intoxication