DIAGNOSIS AND NEW TECHNIQUE FOR GASTRIC EROSION AND ULCER TREATMENT

Aim. To develop and assess the efficiency and safety of a new technique for treatment of gastric erosions and ulcers by means of combining proton pump inhibitor and probiotics. Materials and methods. The results of treatment using the combination of ezomeprasol and lactobacterin were studied in 102 patients including 51 (50,0%) patients with erosive gastritis detected for the first time, 26 (25,5%) – with erosive gastritis relapse, 15 (14,7%) – with gastric ulcer revealed for the first time, 10 (9,8%) – with combination of gastric ulcer and erosions. The control group consisted of 40 patients who were similar by all the indices and treated using the combination of antisecretory and antibacterial drugs: de-nol + amoxicillin + metronidasol+ omeprasol. Results. The diagnostic program including clinical, endoscopic, morphological and immunological investigations allows to determine the significance of microflora in gastric erosions and ulcers and to assess the indications for antibacterial therapy. Conclusion. The combined treatment using ezomeprasol and antagonistically active culture Lactobacterium plantarum 8P-A3 mixed with almagel is highly effective and nontoxic; it has no contraindications and is significantly cheaper than the analogous by their efficiency methods.

Erosion, gastric ulcer, eradication, ezomeprasol, lactobacterin