Assessment of two-year survival rate after acute myocardial infarction in patients with impaired carbohydrate metabolism during novel coronavirus infection pandemic

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Abstract

Relevance. There are limited data on the long-term outcomes of patients with myocardial infarction (MI) and impaired glucose tolerance (IGT) during the novel coronavirus disease (COVID-19) pandemic in 2020.

Objective. To assess the 24-month survival rate among patients with IGT and previous myocardial infarction in 2020 during the COVID-19 pandemic compared to the same period in 2019.

Materials and methods. We assessed the two-year survival rate of patients with MI and IGT from 10/1/2020 to12/10/2020 during the indirect influence of the pandemic compared to the same period in pre-pandemic 2019. The study was single-center, retrospective.

Results. 179 persons in 2020 and 261 persons in 2019 with MI and IGT applied to a regional center to perform percutaneous coronary intervention (PCI center). There was an increase in mortality from MI and IGT from 4.1 % in 2019 to 9.9 % (p = 0.04) in the “pandemic” year of 2020. The relapse-free survival of patients was analyzed using the Kaplan – Meier curve method. By the end of the first year in 2020, 82.1 % of patients remained from the original, and in 2019 – 88.1 %, (p = 0.001), at the end of the 24-month observation period – 78.2 % among patients with MI in 2020 and 83.5 % in 2019, (p = 0.0015).

Conclusions. A retrospective analysis of cases with MI and IGT during a pandemic in Russia showed the worst prognoses for the two-year survival rate among patients, more severe heart attacks with increased number of complications.

About the authors

А. I. Maltsev

Clinical Cardiology Dispensary

Author for correspondence.
Email: nina11-85@mail.ru

Applicant, Department of Polyclinic Therapy, cardiologist

Russian Federation, Perm

N. А. Koryagina

E.A. Vagner Perm State Medical University

Email: nina11-85@mail.ru

MD, PhD, Professor, Department of Polyclinic Therapy

Russian Federation, Perm

V. S. Koryagin

E.A. Vagner Perm State Medical University

Email: nina11-85@mail.ru

student, Faculty of Medicine

Russian Federation, Perm

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Supplementary files

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2. Fig. 1. Time of MVP in patients with MI and NMO depending on the year of hospitalization

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3. Fig. 2. Relapse-free survival in patients with NMO and MI depending on the year of hospitalization

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