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Post a Comment Increase in liver caudate lobe among children: clinical and laboratory features
- Authors: Toropova Е.А.1, Bukina Е.V.1, Shtina I.Е.2, Repetskaya М.N.1
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Affiliations:
- E.A. Vagner Perm State Medical University
- Federal Scientific Center for Medical and Preventive Health Risk Management Technologies,
- Issue: Vol 40, No 6 (2023)
- Pages: 16-23
- Section: Original studies
- URL: https://journals.rcsi.science/PMJ/article/view/254782
- DOI: https://doi.org/10.17816/pmj40616-23
- ID: 254782
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Abstract
Objective. To identify the presence of clinical and laboratory features in children and adolescents with an increase in the caudate lobe of the liver according to ultrasound data.
Materials and methods. The observation group included 37 children and adolescents with enlarged liver caudate lobe (CL) at the age of 8.1 ± 0.67 years, the comparison group included 38 children and adolescents aged 9.2 ± 0.68 years. A comparative analysis of the data of anamnesis, complaints, objective examination, laboratory and ultrasound examinations was performed.
Results. An increase in the size of liver CL was detected with equal frequency in children of both sexes (p = 0.51) without relation to age (p = 0.18). There were no specific complaints characteristic for increased size of the CL. In children with enlarged CL of the liver, obesity (p = 0.034), diffuse changes in the pancreas (p = 0.01), increased activity of AST and GGT (p = 0.025) and a higher average blood leukocyte content (p = 0.04) was registered significantly more often.
Conclusions. An isolated increase in liver CL requires a more detailed assessment of the state of the liver and the general health of a child.
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##article.viewOnOriginalSite##About the authors
Е. А. Toropova
E.A. Vagner Perm State Medical University
Author for correspondence.
Email: toropova.ea@mail.ru
Candidate of Medical Sciences, Associate Professor, Department of Children’s Diseases
Russian Federation, PermЕ. V. Bukina
E.A. Vagner Perm State Medical University
Email: toropova.ea@mail.ru
Associate Professor, Department of Children’s Diseases, Faculty of Medicine
Russian Federation, PermI. Е. Shtina
Federal Scientific Center for Medical and Preventive Health Risk Management Technologies,
Email: toropova.ea@mail.ru
Head of the Laboratory
Russian Federation, PermМ. N. Repetskaya
E.A. Vagner Perm State Medical University
Email: toropova.ea@mail.ru
MD, PhD, Professor, Head of the Department of Children’s Diseases, Faculty of Medicine
Russian Federation, PermReferences
- Detskaya ul'trazvukovaya diagnostika: rukovodstvo. Tom po gastro-enterologii. Pod red. M.I. Pykova. M.: Vidar 2018; 336.
- Rozengaus E.V., Totin L.A., Nesterov D.V. Komp'yuternaya tomografiya pecheni. Analiz dvadcatiletnego opyta. Medicinskaya vizualizaciya 2013; 2: 20–28.
- CHaplygina E.V., Gubar' A.S. Znachenie ob"emnyh pokazatelej pecheni v svyazi s tipom teloslozheniya i polovoj prinadlezhnosti obsledovannyh lic. ZHurnal anatomii i gistopatologii 2017; 1: 101–104.
- CHemezov L.S., Lozinskij A.S. Ob"em pecheni detej i podrostkov po dannym pozhiznennoj vizualizacii. Orenburgskij medicinskij vestnik 2021; 8 (4): 51–55.
- Fovelver S., Genson G.P. Anatomy of the liver arteries for interventional radiology. Diagnostic and interventional imaging 2015; 96 (6): 537–546.
- Korkin A.L., Ugorelova E.A. Diagnosticheskoe znachenie laboratornyh pokazatelej holestaza i fermentativnogo profilya transaminaz dlya ocenki bakterioholii u pacientov s zabolevaniem zhelchevyvodyashchih putej. Vestnik Sur.Gu. Medicina 2016; 4: 26–29.
- Zvonoreva E.B., Men'shova A.V., Kozhevnikova E.V., Tarasova D.P. Rol' grudnogo moloka v razvitii nekon"yugirovannyh zheltuh. Nauchnoe izvestie 2022; 29: 79–83.
- Bokova T.A. Nealkogol'naya zhirovaya bolezn' pecheni i osnovnye komponenty metabolicheskogo sindroma u detej. Eksperimental'naya I klinicheskaya gastroenterologiya 2020; 1: 15–20.
- Dvoryakovskaya G.M., Kutyreva E.N., Dvoryakovskij I.V., Strokova T.V., Ivleva S.A., Kaganov B.S. Nealkogol'naya zhirovaya bolezn' pecheni u detej po dannym ul'trazvukovoj diagnostiki. Ul'trazvukovaya i funkcional'naya diagnostika 2012; 4: 53–61.
- Klinicheskoe rukovodstvo po laboratornym testam. Pod red. N.U. Tica; per. s angl. pod red. V.V. Men'shikova. Moscow : YUNIMED-press 2003; 960.
- Murakami G., Hata F. Human liver caudate lobe and liver segment. AnatSci Int. 2002; 77 (4): 211–24. doi: 10.1046/j.0022-7722.2002.00033.x. PMID: 12557417.
- Dzhumagaziev A.A., Dzhamaev L.S., Bezrukova D.A. Sostoyanie podzheludochnoj zhelezy pri ozhirenii u detej i vzroslyh. Astrahanskij medicinskij zhurnal 2020; 15 (3): 6–15.
- Narkevich A.N., Vinogradov K.A. Metody opredeleniya minimal'no neobhodimogo ob"ema vyborki v medicinskih issledovaniyah. Social'nye aspekty zdorov'ya naseleniya 2019; 65 (6): 10.
- SHerlo SH., Duli Dzh. Zabolevaniya pecheni i zhelchevyvodyashchih putej. M.: GEOTAR Med 2002; 864.
- Kotovich M.M., Luchsheva E.V., Manerov F.K. Nekotorye aspekty gepatosplenomegalii v detskom vozraste. Medicinskij vestnik Severnogo Kavkaza 2009; 2: 37–42.
- Haritonova L.A., Grigor'ev K.I., Zaprudnov A.M. Ot idei k realizacii: Sovremennye uspekhi detskoj gastroenterologii. Eksperimental'naya i klinicheskaya gastroenterologiya 2019; 171 (11): 4–15.
