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Post a Comment Effect of comorbid pathology on the outcome of gastric cancer with Krukenberg metastases in a patient of reproductive age: clinical case
- Authors: Shevlyukova T.P.1, Chernaya V.A.2, Keln A.A.3,2, Shvedsky M.S.3, Shageeva M.R.3
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Affiliations:
- Многопрофильный клинический медицинский центр «Медицинский город»
- Medical Center "Medical City"
- Tyumen State Medical University
- Issue: Vol 39, No 6 (2022)
- Pages: 118-124
- Section: Clinical case
- URL: https://journals.rcsi.science/PMJ/article/view/232323
- DOI: https://doi.org/10.17816/pmj396118-124
- ID: 232323
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Abstract
Objective. To determine the features of the influence of comorbid pathology on the outcome of metastatic gastric cancer in a patient of reproductive age.
Materials and methods. A prospective analysis of a clinical case was carried out on the basis of the Department of Antitumor Drug Therapy № 1 of the Medical Center "Medical City", Tyumen.
Results. The patient’s case, taking into account the data of instrumental examinations, objective examination, general condition of 40 % on the Karnofsky Scale, ECOG-3 (Eastern Cooperative Oncology Group), diagnosis, morphology and complications, was diagnosed as incurable; special methods of antitumor treatment were not indicated. In the current clinical situation, there was used the post-syndrome therapy, prolongation of antiretroviral therapy, examination for searching an infectious agent in the liquor and blood.
Conclusions. Treatment of stage IV gastric cancer is aimed at prolonging the patient's life and improving its quality, stabilizing the disease; its goal is to achieve the same result in terms of quality of life and overall survival as in HIV-negative patients.
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##article.viewOnOriginalSite##About the authors
T. P. Shevlyukova
Многопрофильный клинический медицинский центр «Медицинский город»
Author for correspondence.
Email: tata21.01@mail.ru
ORCID iD: 0000-0002-7019-6630
MD, PhD, Professor, Department of Obstetrics and Gynecology of the Institute of Motherhood and Childhood
Russian Federation, ТюменьV. A. Chernaya
Medical Center "Medical City"
Email: tata21.01@mail.ru
ORCID iD: 0000-0003-0741-7282
Oncologist
Russian Federation, TyumenA. A. Keln
Tyumen State Medical University; Medical Center "Medical City"
Email: tata21.01@mail.ru
ORCID iD: 0000-0002-5071-0604
Candidate of Medical Sciences, Associate Professor, Department of Oncology, Radiology and Radiotherapy of the Institute of Clinical Medicine
Russian Federation, Tyumen; TyumenM. S. Shvedsky
Tyumen State Medical University
Email: tata21.01@mail.ru
ORCID iD: 0000-0002-8854-2773
sixth-year student of the Institute of Clinical Medicine
Russian Federation, TyumenM. R. Shageeva
Tyumen State Medical University
Email: tata21.01@mail.ru
ORCID iD: 0000-0003-4191-2359
sixth-year student of the Institute of Clinical Medicine
Russian Federation, TyumenReferences
- Kit O.I., Samoylenko N.S., Franzyants E.M. Stomach cancer: modern directions of fundamental research. Modern Problems of Science and education 2019; 4: 136 (in Russian).
- Ehren K., Hertenstein C., Kümmerle T. Causes of death in HIV-infected patients from the Cologne-Bonn-Cohort. Infection 2014; 42: 135–140.
- Rohner E., Wyss N., Heg Z. HIV and human herpesvirus 8 co-infection across the globe: systematic review and meta-analysis. Int J Cancer 2016; 138: 45–54.
- Gorbunova V.A., Giyasbeyli S.R., Dadasheva A.E., Mammadov M.K. The frequency of detection of HBsAg in patients with breast, lung and stomach cancer. The World of Viral Hepatitis 2004; 1: 10–11 (in Russian).
- Gotti D., Raffetti E., Albini L. Survival in HIV-infected patients after a cancer diagnosis in the cART era: Results of an Italian Multicenter Study. PLoS One 2014; 9: 124–132.
- Coghill A.E., Shiels M.S., Suneja G., Engels E.A. Elevated cancer-specific mortality among HIV-infected patients in the United States. J Clin Oncol 2015; 33: 2376–2383.
- Podymova A.S., Rassokhin V.V. HIV and oncology. HIV infection and immunosuppression 2017; 2: 100–103 (in Russian).
- Nekrasova A.V. Malignant neoplasms in HIV-infected patients. Malignant tumors 2016; 4: 20 (in Russian).
- Bulatova I.A., Shevlyukova T.P., Shchekotova A.P., Krivtsov A.V. The presence of CAT genetic markers indicates an accelerated rate of progression of liver fibrosis in patients with chronic hepatitis. Experimental and Clinical Gastroenterology 2021; 189: 39–43 (in Russian).
- Bulatova I.A., Shevlyukova T.P., Shchekotova A.P., Krivtsov A.V. Genetic profile of patients with chronic hepatitis C. Pathological Physiology and Experimental Therapy 2022; 66: 35–43 (in Russian).
- Tajibov S.N., Polikarpova S.B., Kochoyan T.M., Kolerev A.S., Kerimov R.A., Berishvili A.I. Metastases of gastric cancer in the ovaries. Survival and prognostic factors. Tumors of the female reproductive system 2016; 4: 57–62 (in Russian).
- Zykova T.A. Some medical and statistical indicators of the prevalence of HIV infection among cancer patients. Malignant tumors 2017; 1: 170 (in Russian).
- Semashko O.G. HIV infection and the risk of developing malignant tumors. New Science: Strategies and Vectors of Development 2016; 3: 58 (in Russian).
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