Role of vitamin D in formation of climacteric syndrome
- Authors: Koval M.V.1, Udachina A.A.1
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Affiliations:
- Ural State Medical University
- Issue: Vol 39, No 6 (2022)
- Pages: 5-10
- Section: Original studies
- URL: https://journals.rcsi.science/PMJ/article/view/232310
- DOI: https://doi.org/10.17816/pmj3965-10
- ID: 232310
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Abstract
Menopause is a physiological period during which involutional processes in the reproductive system predominate in a woman's body. Vitamin D deficiency increases the risk of age-related diseases, so it is important to examine and, if necessary, adjust the level of vitamin D. Purpose of the study. To determine the relationship between vitamin D levels and the severity of menopausal syndrome in postmenopausal women. Materials and methods. A cross-sectional study was conducted, which included data on 150 patients who applied for a gynecological appointment with complaints of manifestations of menopausal syndrome (CS). Results. As a result of the study, it was revealed that out of 150 women with manifestations of menopausal syndrome, the average level of 25(OH)D in the blood serum was 25.3(7.5) ng/ml. At the same time, in 49 (33%) of the surveyed, the content of hydroxyvitamin D was normal, a deficiency was observed in 53 (35%), and in 48 (32%), the indicators corresponded to a deficiency. However, the correlation analysis of the relationship between the level of vitamin D and the severity of the climacteric syndrome did not reveal a statistically significant relationship between the studied parameters (p=0.317). Conclusions. The severity of menopausal syndrome does not depend on the level of vitamin D in the blood, which confirms the leading role of hypoestrogenism in the etiopathogenesis of this condition.
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##article.viewOnOriginalSite##About the authors
M. V. Koval
Ural State Medical University
Email: ariudachina@gmail.com
ORCID iD: 0000-0003-1321-6583
Candidate of Medical Sciences, Associate Professor, Department of Obstetrics and GynecologyRussian Federation, Yekaterinburg
A. A. Udachina
Ural State Medical University
Author for correspondence.
Email: ariudachina@gmail.com
Student
Russian Federation, YekaterinburgReferences
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