Features of diagnostics and treatment of malignant thyroid neoplasms
- Authors: Makarov I.V.1, Pismennyi I.V.1, Pismennyi V.I.1, Galkin R.A.1, Ruzanova A.A.1
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Affiliations:
- Samara State Medical University
- Issue: Vol 39, No 5 (2022)
- Pages: 41-47
- Section: Original studies
- URL: https://journals.rcsi.science/PMJ/article/view/112475
- DOI: https://doi.org/10.17816/pmj39541-47
- ID: 112475
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Abstract
Objective. To analyze diagnostics and treatment of 50 patients operated for thyroid cancer (TC), to assess the information content of classification according to the TIRADS and BETHESDA systems in comparison with the final morphological study of the removed thyroid preparations.
Materials and methods. Patients were divided into 3 groups. The first group – 32 (64 %) patients with a verified thyroid cancer before surgery according to the results of fine needle aspiration puncture biopsy and a confirmed diagnosis after surgery. The second group, 4 (8 %) persons, included patients with a verified thyroid cancer before surgery, but a negative final morphological study. The third group, 14 (28 %) patients with an unverified thyroid cancer before surgery, but a confirmed diagnosis of thyroid cancer according to the results of a final morphological study. To compare the compliance of the TIRADS system with the BETHESDA system, the Kappa index was used.
Results. The highest compliance, 100 %, was found between TIRADS 5 and BETHESDA 5, with a Kappa index of 1.
Conclusions. Comparison of the results of preoperative and final morphological studies showed that the use of TIRADS and BETHESDA classifications is an informative method in diagnostics of thyroid cancer only in 48 % of cases.
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##article.viewOnOriginalSite##About the authors
I. V. Makarov
Samara State Medical University
Author for correspondence.
Email: makarov-samgmu@yandex.ru
ORCID iD: 0000-0002-1068-3330
MD, PhD, Professor, Head of the Department of Surgery of the Institute of Pediatrics
Russian Federation, SamaraI. V. Pismennyi
Samara State Medical University
Email: makarov-samgmu@yandex.ru
ORCID iD: 0000-0003-4684-7955
Assistant, Department of Maxillofacial Surgery and Dental Surgery
Russian Federation, SamaraV. I. Pismennyi
Samara State Medical University
Email: makarov-samgmu@yandex.ru
ORCID iD: 0000-0002-9726-1113
Candidate of Medical Sciences, Associate Professor, Department of Dentistry
Russian Federation, SamaraR. A. Galkin
Samara State Medical University
Email: makarov-samgmu@yandex.ru
ORCID iD: 0000-0003-3665-3161
MD, PhD, Professor, Professor of the Department of Surgery of the Institute of Pediatrics
Russian Federation, SamaraA. A. Ruzanova
Samara State Medical University
Email: makarov-samgmu@yandex.ru
ORCID iD: 0000-0002-1144-6986
third-year student, Institute of Clinical Medicine
Russian Federation, SamaraReferences
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