Features of diagnostics and treatment of thyrotoxicosis in patients with severe comorbid pathology: clinical case

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Abstract

Objective. To demonstrate the stages of diagnostics and successful treatment of thyrotoxicosis in a patient with severe comorbid pathology.

Materials and methods. A clinical case report of a patient with toxic goiter is presented.

Results. To specify the state of the thyroid gland, diagnostic and laboratory methods were applied: ultrasound examination (thyroid volume increased up to 182 cm2, isoechogenic nodule in the left lobe – up to 1 cm, thyroid vascularization increased), spiral computed tomography (picture of diffuse nodular goiter with partial retrosternal location of the left thyroid lobe), hormone studies, the results of which revealed thyrotoxicosis. Thyroidectomy was subsequently carried out. Both thyroid lobes with isthmus were removed step-by-step with technical difficulties and high bleeding of tissues. The patient was discharged in 10 days in a satisfactory state.

Conclusions. Thyrotoxicosis is certainly a complex surgical pathology, in which correct assessment of the diagnosis by instrumental, clinical and laboratory methods is required, as well as successful surgical intervention. Not only normalization of hormonal status of a patient has to be taken into account, but also the possibility of disease relapse, contraindications due to age, physiological status, and comorbid abnormalities.

About the authors

S. N. Styazhkina

Izhevsk State Medical Academy; Republican Clinical Hospital, Surgical Department №1

Email: karmanova-nika@mail.ru

MD, PhD, Professor, Honored Worker of Public Health of UR, Honored Worker of Higher School of the Russian Federation

Russian Federation, Izhevsk; Izhevsk

E. V. Chernyadeva

Republican Clinical Hospital, Endocrinology Department №1

Email: karmanova-nika@mail.ru

endocrinologist, Lecturer-Researcher

Russian Federation, Izhevsk

V. V. Karmanova

Izhevsk State Medical Academy

Author for correspondence.
Email: karmanova-nika@mail.ru

student

Russian Federation, Izhevsk

K. I. Sazhina

Izhevsk State Medical Academy

Email: karmanova-nika@mail.ru

student

Russian Federation, Izhevsk

V. I. Korobeinikov

Republican Clinical Hospital, Surgical Department №1

Email: karmanova-nika@mail.ru

Candidate of Medical Sciences, surgeon of the Highest Qualification Category, Honored Worker of Public Health of UR

Russian Federation, Izhevsk

References

  1. Khamnueva L.Y., Andreeva L.S., Khantakova E.A. Thyrotoxicosis syndrome: etiology, pathogenesis, diagnosis, treatment: textbook. Irkutsk: IGMU 2018; 52 (in Russian).
  2. Petunina H.A., Trukhina L.V. Diseases of the thyroid gland. Moscow: GEOTAR-Media 2011; 74-106 (in Russian).
  3. Stjazhkina S.N., Ledneva A.V., Poryvaeva E.L., Bratchikova K.A., Vershinina N.S. Vlijanie jekologicheskih faktorov na strukturu zabolevanij shhitovidnoj zhelezy v Udmurtii. Nauchnyj al'manah 2015; 11 (4): 149-154 (in Russian).
  4. Styazhkina S.N., Ledneva A.V., Poryvaeva E.L. Assessing Quality of Life in Patients with Graves’ Disease Following Thyroidectomy. Creative surgery and oncology 2019; 9 (1): 26-30.
  5. Stjazhkina S.N., Poryvaeva E.L., Grebneva M.A., Krylova L.R., Pankratova I.A. Psihojemocional'noe sostojanie pacientov s zabolevanijami shhitovidnoj zhelezy v blizhajshem i otdalennom periodah. Sovremennye problemy nauki i obrazovanija. Moscow 2015 (in Russian).

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Copyright (c) 2022 Styazhkina S.N., Chernyadeva E.V., Karmanova V.V., Sazhina K.I., Korobeinikov V.I.

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